天然免疫学热点领域科研抗体(AbD Serotec®)—巨噬细胞标志物抗体
MCA1957识别小鼠细胞表面macrosialin,为人CD68的同源物,是专门表达于组织巨噬细胞的一种重度糖基化的跨膜糖蛋白。
F4/80(MCA497PE)染成红色,B细胞用anti C- 巨噬细胞用anti CD68(MCA1957)染色
D79b(MCA1821A488)染成绿色,细胞核用D-
API复染,呈蓝色
人巨噬细胞标志物抗体
|
||||
产品名称
|
克隆号
|
产品编号
|
形式
|
|
CD11b
|
ICRF44
|
MCA551
|
Pur., A647, A700, Az. Fr., Biot., FITC, RPE, RPE-A647
|
|
CD14
|
UCHM1
|
MCA596
|
Pur., A647, APC, Az. Fr., Biot., FITC, RPE
|
|
CD14
|
TUK4
|
MCA1568
|
Pur., A647, A700, Biot., FITC, LE, PB, RPE, RPE-A647, RPE-A750
|
|
CD14
|
MEM-18
|
MCA2185
|
Pur., FITC, RPE
|
|
CD14
|
61D3
|
MCA2804
|
RPE-Cy5, RPE-Cy5.5
|
|
CD163
|
EDHu-1
|
MCA1853
|
Pur., FITC
|
|
CD169
|
7-239
|
MCA2517
|
Pur., A488, A647, FITC, LE, RPE
|
|
CD200R
|
OX108
|
MCA2282
|
Pur., A488, A647, Biot., FITC, RPE
|
|
CD204
|
Poly
|
AHP563
|
Serum
|
|
CD206
|
15-2
|
MCA2155
|
Pur.
|
|
CD209
|
MR-1
|
MCA2318
|
Pur., A488, A647, Biot., FITC, LE, RPE
|
|
CD31
|
WM59
|
MCA1738
|
Pur., A647, Biot., FITC, RPE
|
|
CD36
|
SMØ
|
MCA722
|
Pur., A647, Az. Fr., FITC
|
|
CD68
|
514H12
|
MCA1815
|
S/N
|
|
CD68
|
KiM7
|
MCA2375F
|
FITC
|
|
Dectin-1
|
BD6
|
MCA4662
|
Pur., A488, A647, FITC, RPE
|
|
Dectin-1
|
GE2
|
MCA4661
|
Pur., A488, A647, FITC, LE, RPE
|
|
Macrophage
|
MAC387
|
MCA874
|
Pur., A488, FITC, LE, RPE
|
|
小鼠巨噬细胞标志物抗体
|
||||
CD11b
|
M1/70.15
|
MCA74
|
Pur., A488, A647, A700, Biot., FITC, LE, RPE, RPE-
A647, RPE-A750, RPE-Cy5 |
|
CD11b
|
5C6
|
MCA711
|
Pur., FITC, LE, RPE
|
|
CD115
|
604B5
|
2E11
|
MCA1898 Pur., Az. Fr., RPE
|
|
CD169
|
MOMA-1
|
MCA947
|
Pur., S/N, A647, FITC
|
|
CD169
|
3D6.112
|
MCA884
|
Pur., FITC, LE
|
|
CD200R
|
OX-110
|
MCA2281
|
Pur., A488, A647, Biot., FITC, LE, RPE
|
|
CD204
|
2F8
|
MCA1322
|
Pur., A488, A647, Biot., FITC, LE, RPE
|
|
CD206
|
MR5D3
|
MCA2235
|
Pur., A488, A647, Biot., FITC, LE, RPE
|
|
CD31
|
ER-MP12
|
MCA2388
|
Pur., A488, A647, Biot., RPE, RPE-A647
|
|
CD36
|
MF3
|
MCA2748
|
Pur., A488, A647, FITC, LE, RPE
|
|
CD68
|
FA-11
|
MCA1957
|
Pur., A488, A647, A700, Az. Fr., Biot., FITC, RPE
|
|
Dectin-1
|
2A11
|
MCA2289
|
Pur., A647, Biot., FITC, LE, RPE
|
|
Dectin-2
|
D2.11E4
|
MCA2415
|
Pur., A488, A647, Biot., FITC, LE, RPE
|
|
F4/80
|
CI:A3-1
|
MCA497
|
Pur., A488, A647, A700, APC, Biot., FITC, LE, PB, RPE, RPE-A647, RPE-A750, S/N
|
|
Ly-6B.2
|
7/4
|
MCA771
|
Pur., A647, A700, Biot., FITC, LE, RPE
|
|
Ly-6C
|
ER-MP20
|
MCA2389
|
Pur., A488, A647, Biot., RPE
|
|
MARCO
|
ED31
|
MCA1849
|
Pur., FITC, RPE
|
|
TREM-1
|
L5-B8.2A12.3A12
|
MCA2578
|
Pur., A488, A647, FITC, LE, RPE
|
|
TREM-2
|
78.18
|
MCA4772
|
Pur., FITC, LE
|
|
大鼠巨噬细胞标志物抗体
|
||||
CD11b
|
OX-42
|
MCA275
|
Pur., A488, A647, A700, Biot., FITC, LE, PB, RPE, RPE-
A647 |
|
CD11b
|
ED7
|
MCA618R
|
Pur.
|
|
CD11b
|
ED8
|
MCA619
|
Pur., FITC, RPE
|
|
CD115
|
604B52E11
|
MCA1898
|
Pur., Az. Fr., RPE
|
|
CD163
|
ED2
|
MCA342
|
Pur., A647, Biot., FITC, LE, RPE
|
|
CD169
|
ED3
|
MCA343
|
Pur.
|
|
CD172a
|
OX41
|
MCA274
|
Pur., Az. Fr., Biot, FITC, RPE
|
|
CD172a
|
ED9
|
MCA620
|
Pur., FITC, RPE
|
|
CD200R1
|
OX-102
|
MCA1959
|
Pur., Biot., FITC, LE, RPE
|
|
CD31
|
TLD-3A12
|
MCA1334
|
Pur., A488, A647, Biot., FITC, LE, RPE
|
|
CD68
|
ED1
|
MCA341
|
Pur., A488, A647, A700, Biot., FITC, RPE
|
荧光多色染色试剂
产品名称
|
克隆号
|
产品编号
|
形式
|
Human CD45/CD14
|
F10-89-4/UCHM1
|
DC008
|
FITC/RPE
|
Mouse IgG2a/IgG2a
|
Negative Control
|
DC013
|
FITC/RPE
|
Mouse Ly6C/CD31
|
ERMP20/ERMP12
|
DC053
|
A488/RPE
|
Mouse Ly6C/CD31
|
ERMP20/ERMP12
|
DC054
|
A488/RPE-A647
|
Mouse CD11b/CD115
|
M1/70.15 / 604B5 2E11
|
DC055
|
A488/RPE
|
Mouse Ly6C/CD115/CD11b
|
ERMP20/604B52E11/M1/70.15
|
TC015
|
A488/RPE/RPE-A647
|
Mouse Ly6C/CD115/CD31
|
ERMP20/604B52E11/ERMP12
|
TC016
|
A488/RPE/RPE-A647
|
Mouse Ly6C/CD115/CD31
|
ERMP20/604B52E11/ERMP12
|
TC017
|
A488/RPE/A647
|
Mouse Ly6C/CD115/CD11b/CD31
|
ERMP20/604B52E11/M1/70.15/ERMP12
|
QC001
|
A488/RPE/RPE-A647/A647
|
AbD Serotec公司 F4/80 产品参考文献
1. Austyn, J.M. and Gordon, S. (1981) F4/80 , a monoclonal antibody directed specifically against the mouse macrophage.Eur. J. Immunol. 11: 805-815.
2. Hume, D.A., Perry, V.H., and Gordon, S. (1984) The Mononuclear Phagocyte System of the Mouse defined by Immunohistochemical Localisation of Antigen F4/80: Macrophages Associated with Epithelia.The Anatomical Record 210: 503-512.
3. Lee, S.H. et al. (1985) Quantitative analysis of total macrophage content in adult mouse tissues. Immunochemical studies with monoclonal antibody F4/80.J. Exp. Med. 161: 475-489.
4. Gordon, S. et al. (1992) Antigen markers of macrophage differentiation in murine tissues.
Curr. Top. Micro. Immunol. 181: 1-37.
5. Uaesoontrachoon, K. et al. (2013) Osteopontin deficiency delays inflammatory infiltration and the onset of muscle regeneration in a mouse model of muscle injury.Dis Model Mech. 6: 197-205.
6. Lin, H. H.et al. (2005) The macrophage F4/80 receptor is required for the induction of antigen-specific efferent regulatory T cells in peripheral tolerance.J. Exp. Med. 201: 1615–1625.
7. Chan, R.J. et al. (2005) Human somatic PTPN11 mutations induce hematopoietic cell hypersensitivity to granulocyte-macrophage colony stimulating factor.Blood. 105: 3737-3742.
8. Pizza, F.X. et al. (2005) Neutrophils contribute to muscle injury and impair its resolution after lengthening contractions in mice.J. Physiol. 562:899-913.
9. Tarallo, V. et al. (2011) The biflavonoid amentoflavone inhibits neovascularization preventing the activity of proangiogenic vascular endothelial growth factors.J Biol Chem. 286: 19641-51.
10. Rivollier, A. et al. (2012) Inflammation switches the differentiation program of Ly6Chi monocytes from antiinflammatory macrophages to inflammatory dendritic cells in the colon.
J Exp Med. 209: 139-55.
11. Hemmi, H. et al. (2009) A new triggering receptor expressed on myeloid cells (Trem) family member,Trem-like 4, binds to dead cells and is a DNAX activation protein 12-linkedmarker for subsets of mouse macrophages and dendritic cells.J Immunol. 182:1278-86.
12. Seitz, O. et al. (2010) Wound Healing in Mice with High-Fat Diet- or ob Gene-Induced Diabetes-Obesity Syndromes: A Comparative Study.Exp Diabetes Res. 2010: 476969.
13. Miao, E.A. et al. (2011) Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.Nat Immunol. 11: 1136-42.
14. Wang, X. et al. (2011) Activation of the cholinergic antiinflammatory pathway ameliorates obesity-induced inflammation and insulin resistance.Endocrinology. 152: 836-46.
15. Cunningham, O. et al. (2009) Microglia and the urokinase plasminogen activator receptor/uPA system ininnate brain inflammation.Glia. 57: 1802-14.
16. Gornicka, A. et al. (2012) Adipocyte hypertrophy is associated with lysosomal permeability both in vivo and in vitro: role in adipose tissue inflammation.Am J Physiol Endocrinol Metab. 303: E597-606.
17. Akbarshahi, H. et al. (2012) Enrichment of Murine CD68(+)CCR2(+) and CD68(+)CD206(+) Lung Macrophages in Acute Pancreatitis-Associated Acute Lung Injury.PLoS One. 7: e42654.
18. Banda, N.K. et al. (1012) Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice.J Immunol. 188: 1469-78.
19. Bonde, A.K. et al. (2012) Intratumoral macrophages contribute to epithelial-mesenchymal transition in solid tumors.BMC Cancer. 12: 35.
20. Choi, K.M. et al. (2010) CD206-positive M2 macrophages that express heme oxygenase-1 protect against diabetic gastroparesis in mice.Gastroenterology. 138: 2399-409,
21. Tamaki, S. et al. (2013) Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction.PLoS One. 8: e68893.
22. Kihira, Y. et al. (2014) Deletion of hypoxia-inducible factor-1a in adipocytes enhances glucagon-like Peptide-1 secretion and reduces adipose tissue inflammation.PLoS One. 9(4):e93856.