Y-01/05/25-Y-27632-小分子化合物

产品名称:Y-27632
产品编号:Y-01/05/25
品牌;StemRD
厂家:StemRD
产品规格:1/5/25mg
储存条件:-80℃
到货时间:2-5天

产品信息

Ras 同源基因-Rho相关螺旋卷曲蛋白激酶(Ras homolog gene/a Rho-associated coiled coil-forming protein kinase,Rho-ROCK)信号途径是中枢神经系统中普遍存在的一条通路,是介导抑制性信号阻断中枢神经细胞再生的重要途径。

Y-27632:
(1R,4r)-4-((R)-1-aminoethyl)-N-(pyridine-4-yl) cyclohexane-carboxamid-2HCl, is a Rho-associated kinase (ROCK) inhibitor. Y-27632 has been shown to prevent apoptosis as well as enhance the survival and cloning efficiency of dissociated human embryonic stem (ES) cells without affecting their pluripotency.

Purity:
Greater than 99% as determined by LC/MS analysis. LC/MS and/or NMR data available upon request.

Biological Activity:
Tested active for culturing human iPS cells in serum-free medium on Matrigel coated plates.