InvivoGenmef-c3h4mC3H/TLR4mut MEF3-7 x 10e6 cells
InvivoGenmef-c3hwtC3H/WT MEF3-7 x 10e6 cells
InvivoGenmef-c57wtC57/WT MEF3-7 x 10e6 cells
InvivoGentlrl-cdac-di-AMP1 mg
InvivoGenvac-cdac-di-AMP VacciGrade™1 mg
InvivoGentlrl-cdgc-di-GMP1 mg
InvivoGenvac-cdgc-di-GMP VacciGrade™1 mg

BX795

TBK1/IKKε inhibitor

BX795 inhibits the catalytic activity of TBK1/IKKε by blocking their phosphorylation. BX795, an aminopyrimidine compound, was developed as an inhibitor of 3-phosphoinositide-dependent kinase 1 (PDK1) [1]. It was recently shown to be a potent inhibitor of the IKK-related kinases, TANK-binding kinase 1 (TBK1) and IKKε, and hence of IRF3 activation and IFN-β production [2, 3]

Citations：

Recent articles using BX795

• 2014 – J Immunol., 192(5):2395-404
  Inflammatory cytokines break down intrinsic immunological tolerance of human primary keratinocytes to cytosolic DNA.
  Chiliveru S, Rahbek SH, Jensen SK, Jørgensen SE, Nissen SK, Christiansen SH, Mogensen TH, Jakobsen MR, Iversen L, Johansen C, Paludan SR
• 2014 – J Immunol., 192(1):492-502
  MPYS/STING-mediated TNF-α, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo.
  Blaauboer SM, Gabrielle VD, Jin L
• 2012 – Hum Gene Ther., 23(10):1090-100
  Inhibition of intracellular anti-viral defense mechanisms augments lentiviral transduction of human natural killer cells: implications for gene therapy.
  Sutlu T, Nyström S, Gilljam M, Slan B, Applequist SE, Alici E

InvivoGen ant-bl-1 Blasticidin (solution) 100 mg (10 x 1 ml)
InvivoGen ant-bl-5 Blasticidin (solution) 500 mg (50 x 1 ml)
InvivoGen ant-bl-5b Blasticidin (solution) 500 mg (50 ml bottle)
InvivoGen tlrl-bx7 BX795 5 mg
InvivoGen tlrl-c12dap C12-iE-DAP 1 mg
InvivoGen mef-c3h4m C3H/TLR4mut MEF 3-7 x 10e6 cells
InvivoGen mef-c3hwt C3H/WT MEF 3-7 x 10e6 cells
InvivoGen mef-c57wt C57/WT MEF 3-7 x 10e6 cells
InvivoGen tlrl-cda c-di-AMP 1 mg
InvivoGen vac-cda c-di-AMP VacciGrade™ 1 mg
InvivoGen tlrl-cdg c-di-GMP 1 mg
InvivoGen vac-cdg c-di-GMP VacciGrade™ 1 mg
InvivoGen tlrl-cdi c-di-IMP 1 mg
InvivoGen tlrl-cdu c-di-UMP 1 mg
InvivoGen ant-cls Celastrol 1 mg
InvivoGen vac-cfa-10 CFA 10 ml
InvivoGen vac-cfa-60 CFA 6 x 10 ml
InvivoGen gt115-11 ChemiComp GT115 5 X 0.1 ml
InvivoGen gt115-21 ChemiComp GT115 5 X 0.2 ml
InvivoGen gt116-11 ChemiComp GT116 5 X 0.1 ml
InvivoGen gt116-21 ChemiComp GT116 5 X 0.2 ml
InvivoGen tlrl-chq Chloroquine 250 mg
InvivoGen inh-ci99 CI-994 10 mg
InvivoGen tlrl-c75 CL075 500 µg
InvivoGen tlrl-c75-5 CL075 5 mg
InvivoGen tlrl-c97 CL097 500 µg
InvivoGen tlrl-c97-5 CL097 5 mg
InvivoGen tlrl-c264e CL264 500 µg
InvivoGen tlrl-c264e-5 CL264 5 mg
InvivoGen tlrl-bc264 CL264 Biotin 100 µg
InvivoGen tlrl-fc264 CL264 FITC 100 µg
InvivoGen tlrl-rc264 CL264 Rhodamine 100 µg
InvivoGen tlrl-c307 CL307 500 µg
InvivoGen tlrl-c401 CL401 500 µg
InvivoGen tlrl-c419 CL419 500 µg
InvivoGen tlrl-c531 CL531 500 µg
InvivoGen tlrl-c572 CL572 500 µg
InvivoGen tlrl-cli95 CLI-095 1 mg
InvivoGen mabg1-ctrlm Control IgG1 100 µg
InvivoGen mabg2a-ctrlm Control IgG2a 100 µg
InvivoGen mabg2b-ctrlm Control IgG2b 100 µg
InvivoGen tlrl-cp69 CP-690550 5 mg
InvivoGen tlrl-cppd CPPD crystals 5 mg
InvivoGen tlrl-cura Curdlan AL 1 g
InvivoGen tlrl-cyca Cyclosporin A 100 mg
InvivoGen tlrl-dex Dexamethasone 100 mg
InvivoGen tlrl-dmx DMXAA 5 mg
InvivoGen tlrl-ecdna dsDNA-EC 200 µg
InvivoGen tlrl-ssec E. coli ssDNA / LyoVec™ 200 µg
InvivoGen tlrl-eve Everolimus 5 mg
InvivoGen fas-am-s500 Fast-Media® Amp Agar 500 pouches
InvivoGen fas-am-s Fast-Media® Amp Agar 30 pouches
InvivoGen fas-am-b500 Fast-Media® Amp LB 500 pouches
InvivoGen fas-am-b Fast-Media® Amp LB 30 pouches
InvivoGen fas-am-l500 Fast-Media® Amp TB 500 pouches
InvivoGen fas-am-l Fast-Media® Amp TB 30 pouches
InvivoGen fas-am-x Fast-Media® Amp XGal Agar 20 pouches
InvivoGen fas-s500 Fast-Media® Base Agar 500 pouches
InvivoGen fas-s Fast-Media® Base Agar 30 pouches
InvivoGen fas-b500 Fast-Media® Base LB 500 pouches
InvivoGen fas-b Fast-Media® Base LB 30 pouches
InvivoGen fas-bl-s Fast-Media® Blas Agar 20 pouches
InvivoGen fas-bl-l Fast-Media® Blas TB 20 pouches
InvivoGen fas-bl-x Fast-Media® Blas XGal Agar 20 pouches
InvivoGen fas-hg-s Fast-Media® Hygro Agar 20 pouches
InvivoGen fas-hg-l Fast-Media® Hygro TB 20 pouches
InvivoGen fas-hg-x Fast-Media® Hygro XGal Agar 20 pouches

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