Recombinant human E-cadherin/CDH1 protein
货号：
P02351
品牌：
Jinpan
产品简介
| 基因名 | E-cadherin/CDH1 |
| 英文全称 | cadherin 1 |
| 别称 | cadherin 1 |
| 中文名称 | 钙粘蛋白-1 |
| Uniprot | P12830 |
| GeneID | 999 |
| 交叉反应(推测) | Human Mouse Rat (Bovine Dog Chicken Gorilla) |
| 氨基酸大小 | 27kDa |
| 表达氨基酸 | 373-622aa |
| Background | The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism.The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH.The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit.This gene is predominantly expressed in the heart and skeletal muscles.Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Bioactive | Unknown. (Ban’t be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug 50ug 100ug 1mg |