Recombinant human PPIF protein
货号：
P03730
品牌：
Jinpan
产品简介
| 基因名 | PPIF |
| 英文全称 | peptidylprolyl isomerase F |
| 别称 | CYP3;CyP-M;Cyp-D;CypD |
| 中文名称 | 肽酰脯氨酰异构酶F |
| Uniprot | P30405 |
| GeneID | 10105 |
| 交叉反应(推测) | Human Mouse Rat (Bovine) |
| 氨基酸大小 | 22kDa |
| 表达氨基酸 | 1-207aa |
| Background | PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.Involved in regulation of the mitochondrial permeability transition pore (mPTP).It is proposed that its association with the mPTP is masking a binding site for inhibiting inorganic phosphate (Pi) and promotes the open probability of the mPTP leading to apoptosis or necrosis; the requirement of the PPIase activity for this function is debated.In cooperation with mitochondrial TP53 is involved in activating oxidative stress-induced necrosis.Involved in modulation of mitochondrial membrane F1F0 ATP synthase activity and regulation of mitochondrial matrix adenine nucleotide levels.Has anti-apoptotic activity independently of mPTP and in cooperation with BCL2 inhibits cytochrome c-dependent apoptosis. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban’t be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug 50ug 100ug 1mg |