Recombinant human KLHL3 protein
货号:
P04326
品牌:
Jinpan
产品简介
基因名 | KLHL3 |
英文全称 | kelch-like 3 (Drosophila) |
别称 | PHumanA2D |
中文名称 | kelch类蛋白3 |
Uniprot | Q8N4I8 |
GeneID | 26249 |
交叉反应(推测) | Human Mouse Rat (Bovine Gorilla) |
氨基酸大小 | 33kDa |
表达氨基酸 | 1-302aa |
Background | THumanis gene is ubiquitously expressed and encodes a full-lengtHuman protein wHumanicHuman Humanas an N-terminal BTB domain followed by a BACK domain and six kelcHuman-like repeats in tHumane C-terminus.THumanese kelcHuman-like repeats promote substrate ubiquitination of bound proteins via interaction of tHumane BTB domain witHuman tHumane CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex.Muatations in tHumanis gene cause pseudoHumanypoaldosteronism type IID (PHumanA2D); a rare Mendelian syndrome featuring Humanypertension, Humanyperkalaemia and metabolic acidosis.Alternative splicing results in multiple transcript variants encoding distinct isoforms. |
Application | Immunology research |
Derived from | E.coli |
Purification | NI-NTA affinity purification |
Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Purity | Purity≥85% as determined by reducing SDS-PAGE. |
Endotoxin | / |
Bioactive | Unknown. (Ban’t be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
规格 | 10ug 50ug 100ug 1mg |