盐酸布替萘芬

盐酸布替萘芬

货号:
IB2680

品牌:
Jinpan

盐酸布替萘芬

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盐酸布替萘芬

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产品简介
有效期 2年
EC EINECS 642-354-4
MDL MFCD00917064
别名 盐酸丁萘芬;KP-363
英文名称 Butenafine Hydrochloride
CAS 101827-46-7
分子式 C23H27N·HCl
分子量 353.19
储存条件 -20℃
纯度 ≥98%
外观(性状) White to off-white crystalline powder
单位
生物活性 Butenafine hydrochloride, N-4-tert-butylbenzyl-N-methyl-1-naphthalenemethylamine hydrochloride (butenafine), is a novel antifungal agent of the class of benzylamine derivatives. [1]
In Vivo The concentrations of butenafine in animal skin at 24 and 48 h after application of 0.2 ml of a 1% solution were several hundred times higher than those required to kill T. mentagrophytes and M. canis. The good efficacy of butenafine against dermatophytosis may be attributable to its fungicidal activity and long retention in the skin after topical application.[1]
SMILES CN(CC1=CC=C(C(C)(C)C)C=C1)CC2=C3C=CC=CC3=CC=C2.[H]Cl
靶点 Fungal
数据来源文献 [1]. Arika T, Yokoo M, Hase T, Maeda T, Amemiya K, Yamaguchi H. Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs. Antimicrob Agents Chemother. 1990 Nov;34(11):2250-3.
规格 500mg

是一种苄胺类抗真菌药物,通过抑制甾醇合成,通过抑制角鲨烯环氧酶,而发挥作用。