盐酸布替萘芬
货号：
IB2680
品牌：
Jinpan
暂无详情
暂无详情
产品简介
| 有效期 | 2年 |
| EC | EINECS 642-354-4 |
| MDL | MFCD00917064 |
| 别名 | 盐酸丁萘芬；KP-363 |
| 英文名称 | Butenafine Hydrochloride |
| CAS | 101827-46-7 |
| 分子式 | C23H27N·HCl |
| 分子量 | 353.19 |
| 储存条件 | -20℃ |
| 纯度 | ≥98% |
| 外观（性状） | White to off-white crystalline powder |
| 单位 | 瓶 |
| 生物活性 | Butenafine hydrochloride, N-4-tert-butylbenzyl-N-methyl-1-naphthalenemethylamine hydrochloride (butenafine), is a novel antifungal agent of the class of benzylamine derivatives. [1] |
| In Vivo | The concentrations of butenafine in animal skin at 24 and 48 h after application of 0.2 ml of a 1% solution were several hundred times higher than those required to kill T. mentagrophytes and M. canis. The good efficacy of butenafine against dermatophytosis may be attributable to its fungicidal activity and long retention in the skin after topical application.[1] |
| SMILES | CN(CC1=CC=C(C(C)(C)C)C=C1)CC2=C3C=CC=CC3=CC=C2.[H]Cl |
| 靶点 | Fungal |
| 数据来源文献 | [1]. Arika T, Yokoo M, Hase T, Maeda T, Amemiya K, Yamaguchi H. Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs. Antimicrob Agents Chemother. 1990 Nov;34(11):2250-3. |
| 规格 | 500mg |
是一种苄胺类抗真菌药物，通过抑制甾醇合成，通过抑制角鲨烯环氧酶，而发挥作用。