8-Bromo-cAMPCAS号： 76939-46-3分子式： C10H10BrN5NaO6P分子量： 430.08描述纯度储存/保存方法别名外观可溶性/溶解性靶点In vitro(体外研究)
| 产品描述 | |
| 描述 |
8-Bromo-cAMP is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase, but resistant to degradation by cyclic AMP phosphodiesterase. |
| 纯度 |
＞98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
8-溴腺苷-3′,5′-环单磷酸钠; 8-Bromo-cAMP sodium salt；8-Br-Camp sodium salt
|
| 外观 |
off-white powder
|
| 可溶性/溶解性 |
DMSO : 35 mg/mL (81.38 mM), warmed
Water : 80 mg/mL (186.01 mM), warmed |
| 生物活性 | |
| 靶点 |
PKA
|
| In vitro(体外研究) |
8-Bromo-cAMP improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. In bronchial epithelial cells, 8-Bromo-cAMP decreases HDE-stimulated tumor necrosis factor (TNF)-α-converting enzyme (TACE; ADAM-17) activity and subsequent TNF-α release.
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分子结构图
