A-796260 (Item No. 11606) is a synthetic cannabinoid (CB) that shows high selectivity for the CB₂ receptor (K_i = 0.77 nM) over the CB₁ receptor (K_i = 2,100 nM).¹ It also shows efficacy in vivo in models of inflammatory, post-operative, neuropathic, and osteoarthritic pain, activities which are selectively blocked by CB₂ receptor-selective antagonists.² A-796260 degradant is an impurity that may be produced in the synthesis of A-796260. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.

≥95%

Store at -20℃

LTI-258 Degradant;

1.Poso, A. and Huffman, J.W. Targeting the cannabinoid CB₂ receptor: Modelling and structural determinants of CB₂ selective ligands. British Journal of Pharmacology 153(2), 335-346 (2008).

2.Yao, B.B.,Hsieh, G.C.,Frost, J.M., et al. In vitro and in vivo characterization of A-796260: A selective cannabinoid CB₂ receptor agonist exhibiting analgesic activity in rodent pain models. British Journal of Pharmacology 153(2), 390-401 (2008).