A 425619CAS号： 581809-67-8分子式： C18H14F3N3O分子量： 345.33描述储存/保存方法可溶性/溶解性靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
A 425619 is a potent TRPV1 antagonist
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:34.5 mg/mL (100 mM)
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| 生物活性 | |
| 靶点 |
TRPV1:3-9 nM
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| In vivo(体内研究) |
systemic administration of the TRPV1 antagonist, A-425619, reversed the decrease in digging behavior induced by CFA injection, further confirming the role of TRPV1, expressed by knee neurons, in acute inflammatory joint pain.
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