BMT-124110CAS号： 1679371-59-5分子式： C21H27N3O3分子量： 369.46描述纯度储存/保存方法可溶性/溶解性靶点In vitro(体外研究)In vivo(体内研究)
| 产品描述 | |
| 描述 |
BMT-124110 is a selective AAK1 inhibitor (IC50: 0.9 nM) with antinociceptive activity. BMT-090605 inhibited BMP-2 induced protein kinase BIKE with IC50 of 17 nM. BMT-090605 inhibits cyclin G-associated kinase GAK with an IC50 of 99 nM.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:27.5 mg/mL (74.43 mM)
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| 生物活性 | |
| 靶点 |
AAK1:0.9 nM, GAK:99 nM
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| In vitro(体外研究) |
BMT-124110 presents a cellular IC50 of 3.2 nM for AAK1[1].
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| In vivo(体内研究) |
BMT-124110 is added directly to the spine by microion electrophoresis. Wind-induced activity decreased in 10 of the 14 animals.[1]
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