SS-208CAS号： 2245942-72-5分子式： C13H11Cl2N3O4分子量： 344.15描述纯度储存/保存方法可溶性/溶解性靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
SS-208 is a selective inhibitor of HDAC6 (IC50 = 12 nM) with anti-tumor activity. SS-208 shows selectivity over other HDAC subtypes.
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| 纯度 |
98%
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| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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| 基本信息 | |
| 可溶性/溶解性 |
DMSO:100 mg/mL (290.6 mM)
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| 生物活性 | |
| 靶点 |
HDAC7:8.34 μM, HDAC5:6.91 μM, HDAC11:5.12 μM, HDAC1:1.39 μM, HDAC8:1.23 μM, HDAC6:12 nM
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| In vivo(体内研究) |
In C57BL/6 mice injected immunogenic murine SM1 melanoma cells, SS-208 (25 mg/kg; i.p.) causes a significant reduction of the tumor growth[1].
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