AMG-208CAS号: 1002304-34-8分子式: C22H17N5O2分子量: 383.4描述纯度储存/保存方法可溶性/溶解性参考文献
产品描述 | |
描述 |
AMG 208 is a highly selective c-Met inhibitor with IC50 of 9 nM. Phase 1. |
纯度 |
>98%
|
储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
|
基本信息 | |
可溶性/溶解性 |
体外:
DMSO 0.25mg/mL(0.65mM) Water <1mg>Ethanol <1mg> 1%DMSO+30%polyethyleneglycol+1%Tween80 30mg/mL |
参考文献 | |
参考文献 |
[1] Albrecht BK, et al. J Med Chem. 2008, 51(10), 2879-2882. [2] Boezio AA, et al. Bioorg Med Chem Lett. 2009, 19(22), 6307-6312. [3] Liu X, et al. Trends Mol Med. 2010,16(1), 37-45. |
分子结构图