Arbutin 熊果苷
MDL | MFCD00016915 |
EC | EINECS 207-850-3 |
别名 | β-熊果苷;熊果酚甙; 熊果素;Arbutin |
英文名称 | β-Arbutin |
CAS | 497-76-7 |
分子式 | C12H16O7 |
分子量 | 272.25 |
纯度 | HPLC≥98% |
单位 | 瓶 |
SMILES | O[C@H]([C@H]([C@@H]([C@@H](CO)O1)O)O)[C@@H]1OC2=CC=C(O)C=C2 |
靶点 | Tyrosinase |
规格 | 20mg 10mM*1mL (in DMSO) 100mg |
是一种糖苷,可抑制酪氨酸酶,阻止黑色素生成。
使用本产品的应用案例(仅供参考)
In Vivo
Rat(Arbutin 50mg/kg,口服,2次/天,3天)
Seventy rats were randomly divided into 7 groups (female and male in equal numbers for each group): control group(8, C), SCM model group (12, SCM), AI treated group (10, AI,200 mg kg−1), CY extract treated group (10, CY, 1630 mg kg−1),Ade treated group (10, Ade, 50 mg kg−1), Arb treated group (10,Arb, 50 mg kg−1) and All treated group (10, All, 50 mg kg−1).The SCM model was induced by subcutaneous injection of LPS at a dose of 10 mg kg−1. The drugs were orally administered twice a day for 3 days, respectively. The C and SCM groups were orally administered with the same volume of distilled water in the meantime. All rats were sacrificed after the detection of the cardiac function and the blood sample was obtained from the abdominal aorta.
来源文献:Zhou N , Zeng MN , Li K , Yang YY , Bai ZY , Zheng XK , Feng WS . An integrated metabolomic strategy for the characterization of the effects of Chinese yam and its three active components on septic cardiomyopathy. Food Funct. 2018 Sep 19;9(9):4989-4997. doi: 10.1039/c8fo00688a. PMID: 30187904.