环吡酮胺

环吡酮胺

货号:
IC2740

品牌:
Jinpan

环吡酮胺

暂无详情

环吡酮胺

暂无详情
产品简介
有效期 2年
EC EINECS 249-577-2
MDL MFCD00599441
InChIKey SCKYRAXSEDYPSA-UHFFFAOYSA-N
InChI InChI=1S/C12H17NO2/c1-9-7-11(13(15)12(14)8-9)10-5-3-2-4-6-10/h7-8,10,15H,2-6H2,1H3
PubChem CID 2749
别名 环匹罗司;环匹罗司胺
英文名称 Ciclopirox
CAS 29342-05-0
分子式 C12H17NO2
分子量 207.27
储存条件 2-8℃
纯度 ≥98%
外观(性状) White to light yellow Powder
单位
In Vitro In a study conducted to further elucidate Ciclopirox’s mechanism, several Saccharomyces cerevisiae mutants were screened and tested. Results from interpretation of the effects of both the drug treatment and mutation suggested that Ciclopirox may exert its effect by disrupting DNA repair, cell division signals and structures (mitotic spindles) as well as some elements of intracellular transport[2].
SMILES CC(C=C(C1CCCCC1)N2O)=CC2=O
靶点 Fungal
数据来源文献 [1]. Niewerth, M., et al., Ciclopirox olamine treatment affects the expression pattern of Candida albicans genes encoding virulence factors, iron metabolism proteins, and drug resistance factors. Antimicrob Agents Chemother, 2003. 47(6): p. 1805-17.
[2]. Leem, S.H., et al., The possible mechanism of action of ciclopirox olamine in the yeast Saccharomyces cerevisiae. Mol Cells, 2003. 15(1): p. 55-61.
规格 25mg 50mg 100mg

是一种抗真菌化合物。