蛙皮素
货号：
IB1790
品牌：
Jinpan
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产品简介
| 有效期 | 2年 |
| 描述 | 是一种十四肽，在胃泌素释放和G蛋白受体活化中起重要作用。 |
| MDL | MFCD00167514 |
| 别名 | 铃蟾肽 |
| 英文名称 | Bombesin |
| CAS | 31362-50-2 |
| 分子式 | C71H110N24O18S |
| 分子量 | 1619.85 |
| 储存条件 | -20℃ |
| 纯度 | ≥97% |
| 外观（性状） | Powder |
| 单位 | 瓶 |
| 生物活性 | Bombesin, a tetradecapeptide, plays an important role in the release of gastrin and the activation of G-protein receptors[1]. |
| In Vitro | Bombesin is a tetradecapeptide with a COOH terminus ending in Gly-His-Leu-Met-NH2 and subsequently is shown to closely resemble two mammalian bombesin -related peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB)[1]. Bombesin is found to have stimulatory effects upon gastric and pancreatic secretions, release of gastrointestinal hormones, gallbladder contraction and bronchoconstriction. It is present in amphibian gastric endocrine cells, avian proventriculus endocrine cells and avian brain. In mammals it is present mainly in nerve cells and fibers. The only mammalian endocrine cell shown to date to have bombesin is the P-cell in fetal lung. Bombesin is also found in mammalian brain, with its highest concentration in the hypothalamus[2]. |
| 靶点 | Others |
| 数据来源文献 | [1]. Gonzalez N, et al. Bombesin-related peptides and their receptors: recent advances in their role in physiology and disease states. Curr Opin Endocrinol Diabetes Obes. 2008 Feb;15(1):58-64. [2]. Chejfec G, et al. Bombesin in human neuroendocrine (NE) neoplasms. Peptides. 1985;6 Suppl 3:107-12. |
| 规格 | 1mg |