盐酸安他唑啉

盐酸安他唑啉

货号:
IA3350

品牌:
Jinpan

盐酸安他唑啉

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产品简介
有效期 2年
描述 是一种乙二胺类似物,具有组胺H1拮抗活性。
MDL MFCD00058145
EC EINECS 219-719-8
InChIKey SWKDMSRRIBZZAY-UHFFFAOYSA-N
InChI InChI=1S/C17H19N3.ClH/c1-3-7-15(8-4-1)13-20(14-17-18-11-12-19-17)16-9-5-2-6-10-16;/h1-10H,11-14H2,(H,18,19);1H
PubChem CID 17275
别名 2-(N-苄基苯胺基甲基)-2-咪唑啉盐酸盐N-苯基-N-苄基-4,5-二氢-1H-咪唑-2-甲胺盐酸盐
英文名称 Antazoline Hydrochloride
CAS 2508-72-7
分子式 C17H19N3·HCl
分子量 301.81
储存条件 RT
纯度 ≥98%
外观(性状) White to off-white Solid
单位
生物活性 Antazoline hydrochloride is a first-generation antihistamine with anticholinergic properties, and it is commonly used to relieve nasal congestion and in eye drops. [1]
In Vitro We found that arbidol hydrochloride and antazoline hydrochloride can effectively reduce HBV DNA in the extracellular supernatant in a dose-dependent manner, with EC50 of 4.321 μmol/L and 2.910 μmol/L in HepAD38 cells, respectively. Moreover, antazoline hydrochloride also has a significant inhibitory effect on HBV DNA in the extracellular supernatant of Huh7 cells, with an EC50 of 2.349 μmol/L.[1]
SMILES [H]Cl.C1(CN(C2=CC=CC=C2)CC3=CC=CC=C3)=NCCN1
靶点 Histamine Receptor
数据来源文献 [1]Repurposing of Antazoline Hydrochloride as an Inhibitor of Hepatitis B Virus DNA Secretion[J]. Virologica Sinica:1-9.
规格 50mg 100mg