4-联苯乙酸
货号：
IB2240
品牌：
Jinpan
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产品简介
| 有效期 | 2年 |
| MDL | MFCD00004351 |
| EC | EINECS 227-233-2 |
| InChIKey | QRZAKQDHEVVFRX-UHFFFAOYSA-N |
| InChI | InChI=1S/C14H12O2/c15-14(16)10-11-6-8-13(9-7-11)12-4-2-1-3-5-12/h1-9H,10H2,(H,15,16) |
| PubChem CID | 3332 |
| 别名 | 4-二苯基乙酸 |
| 英文名称 | 4-Biphenylacetic Acid |
| CAS | 5728-52-9 |
| 分子式 | C14H12O2 |
| 分子量 | 212.24 |
| 储存条件 | RT |
| 纯度 | ≥98% |
| 外观（性状） | White to off-white Solid |
| 单位 | 瓶 |
| 生物活性 | 4-Biphenylacetic acid (BPAA) is a prostaglandin-synthesis inhibitor. [1] |
| In Vitro | In vitro, BPAA inhibited prostaglandin production from arachidonic acid in cell-free preparations of rabbit uvea. It is suggested that BPAA may be useful for the therapy of ocular inflammatory disease.[1] |
| In Vivo | Topically applied, BPAA inhibited arachidonic acid, but not prostaglandin E-induced increases in rabbit intraocular pressure (IOP). BPAA inhibited the IOP response to alkali burn and altered IOP changes following paracentesis.[1]4-Biphenylacetic acid (BPAA） markedly inhibits the ocular effects of both chemically and mechanically induced trauma[1]. |
| SMILES | O=C(O)CC1=CC=C(C2=CC=CC=C2)C=C1 |
| 靶点 | Others |
| 数据来源文献 | [1] Tolman EL, et al. Invest Ophthalmol. 1976, 15(12):1005-8. |
| 规格 | 500mg |
是一种有效的非甾体抗炎化合物，可用于肌肉炎症和关节炎的相关研究。