皂皮酸
货号：
IQ0110
品牌：
Jinpan
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产品简介
| 有效期 | 2年 |
| EC | EINECS 211-149-8 |
| 别名 | 皂树酸；皂树皮酸 |
| 英文名称 | Quillaic Acid |
| CAS | 631-01-6 |
| 分子式 | C30H46O5 |
| 分子量 | 486.68 |
| 储存条件 | 2-8°C |
| 纯度 | ≥98% |
| 外观（性状） | White Powder |
| 单位 | 瓶 |
| 生物活性 | Quillaic acid is the major aglycone of the widely studied saponins of the Chilean indigenous tree Quillaja saponaria Mol. [2] |
| In Vivo | A series of quillaic acid derivatives were prepared and subjected to topical assays for the inhibition of inflammation induced by arachidonic acid or phorbol ester.Quillaic acid exhibited strong topical anti-inflammatory activity in both models.[2] |
| SMILES | OC([C@]1(CCC(C)(C)C2)[C@]2([H])C3=CC[C@@]4([H])[C@@](C)(CC[C@]5([H])[C@@]4(CC[C@H](O)[C@@]5(C)C=O)C)[C@]3(C)C[C@H]1O)=O |
| 靶点 | Others |
| 细胞实验 | Materials and methods: The samples were assessed in mice using the topical tail-flick and i.p. hot-plate tests, respectively.The results of the present study demonstrated that Quillaja saponaria saponins, quillaic acid, its methyl ester, and one of the oxidized derivatives of the latter, elicit dose-dependent antinociceptive effects in two murine thermal models.[1] |
| 数据来源文献 | [1]. Arrau S, et al. Antinociceptive activity of Quillaja saponaria Mol. saponin extract, quillaic acid and derivatives in mice. J Ethnopharmacol. 2011 Jan 7;133(1):164-7. [2]. Rodríguez-Díaz M, et al. Topical anti-inflammatory activity of quillaic acid from Quillaja saponaria Mol. and some derivatives. J Pharm Pharmacol. 2011 May;63(5):718-24. |
| 规格 | 5mg |
是一种生物活性化合物，具有多种生物学活性。