Poloxamer 407;泊洛沙姆407
货号:
IP9010
品牌:
Jinpan
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产品简介
MDL | MFCD00082049 |
EC | EINECS 618-355-0 |
CAS | 9003-11-6 |
储存条件 | Powder : 2-8℃, 2 years; -20℃, 3 years |
单位 | 瓶 |
In Vivo | In order to efficiently transfer the Adeno-associated virus (AAV) into the vein graft walls and avoid any potential systemic side effects, we used a local delivery method by using poloxamer-407 (Jinpan, Beijing China) with trypsin as our previously described [14,15,17]. Briefly, after end to end anastomosis of the vein segment to common carotid artery, 30ul AAV6-anti-miR-92a or AAV6-control (Shanghai GeneChem, Co., Ltd. Shanghai, China) fluid was preloaded into 120 μl 25% poloxamer-407 pluronic gel containing 0.25% trypsin at 4?C, and was gently painted around the grafted vein segments.[1] |
数据来源文献 | [1]. Zhong CM, Li S, Wang XW, Chen D, Jiang ZL, Zhang C, He XJ, Huang C, Jiang YJ, Wu QC. MicroRNA-92a -mediated endothelial to mesenchymal transition controls vein graft neointimal lesion formation. Exp Cell Res. 2021 Jan 1;398(1):112402 |
规格 | 500mg 1g |
是非离子型表面活性剂,有特殊的反向热胶凝作用,刺激性小,生物相容性好,是一个理想的药物控释材料