Betamethasone Dipropionate；倍他米松二丙酸酯
货号：
IB2140
品牌：
Jinpan
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产品简介
| MDL | MFCD00133140 |
| EC | EINECS 227-005-2 |
| InChIKey | CIWBQSYVNNPZIQ-XYWKZLDCSA-N |
| InChI | InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1 |
| PubChem CID | 21800 |
| 别名 | 丙酸倍他米松 |
| CAS | 5593-20-4 |
| 分子式 | C28H37FO7 |
| 分子量 | 504.59 |
| 储存条件 | 2-8℃ |
| 纯度 | ≥98% |
| 单位 | 瓶 |
| 生物活性 | Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.[1] |
| SMILES | C[C@@]12[C@](C[C@H](C)[C@]2(OC(CC)=O)C(COC(CC)=O)=O)([H])[C@]3([H])CCC4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C1)=O |
| 靶点 | Glucocorticoid Receptor |
| 数据来源文献 | 1. Park JM, et al. J Am Acad Dermatol. 2013 Sep;69(3):492-3. |
| 规格 | 250mg 500mg |
是糖皮质激素类固醇，具有抗炎和免疫抑制特性。