羧甲基纤维素钠

羧甲基纤维素钠

货号:
IS9000

品牌:
Jinpan

产品简介
MDL MFCD00081472
EC EINECS 900-432-4
别名 CarboxymethylCellulose;羧甲基醚纤维素钠盐
英文名称 Sodium Carboxymethyl Cellulose
CAS 9004-32-4
分子式
储存条件 Powder : 2-8℃, 2 years; -20℃, 3 years
纯度 Viscosity:800-1200mPa.s
单位
靶点 Others
规格 5g

是纤维素羧甲基醚的钠盐,常用作黏稠剂,糊料和阻隔剂。也可用做药物的助溶剂或载体。

使用本产品的应用案例(仅供参考

In Vivo

Mice(ight-week-old male DBA/2J mice),0.5% Na-CMC,灌胃

The mice were randomly divided into six groups (n = 6): normal mice group (NC); diabetic mice group (DM); Fer-1 intraperitoneal injected diabetic mice group (Fer-1); 1% dimethyl sulfoxide (DMSO) intraperitoneal injected diabetic mice group (vehicle-P); fenofibrate intragastric administrated diabetic mice group (Fn); 0.5% sodium carboxymethyl cellulose (Na-CMC; Jinpan,Beijing, China) intragastric administrated diabetic mice group (vehicleG). During the duration of 12-week treatment,  the diabetic mice in the Fn and vehicle-G groups received intragastric treatment of fenofibrate (100 mg/kg, dissolved in 0.5% Na-CMC) and 0.5% Na-CMC every day, respectively. 

来源文献:Li S, Zheng L, Zhang J, Liu X, Wu Z. Inhibition of ferroptosis by up-regulating Nrf2 delayed the progression of diabetic nephropathy. Free Radic Biol Med. 2021 Jan;162:435-449. doi: 10.1016/j.freeradbiomed.2020.10.323. Epub 2020 Nov 2. PMID: 33152439.