Gabapentin hydrochloride；加巴喷丁盐酸盐
货号：
IG1130
品牌：
Jinpan
暂无详情
产品简介
| MDL | MFCD00101985 |
| EC | EINECS 262-075-8 |
| 别名 | GabapentinHCl;Gabarone |
| 英文名称 | Gabapentin hydrochloride |
| CAS | 60142-95-2 |
| 分子式 | C9H17NO2.HCl |
| 分子量 | 207.7 |
| 纯度 | ≥98% |
| 单位 | 瓶 |
| 生物活性 | 是GABA类似物，可用于缓解神经性疼痛[1]。 |
| In Vitro | Gabapentin is a major inhibitory neurotransmitter that functions by binding to the GABA receptors located in the spinal cord. Gabapentin also binds to a novel site on voltage-sensitive Ca2+ channels. Additionally, Gabapentin demonstrates inhibition of dopamine release from caudate nucleus, prevent neuronal cell death, and is antinociceptive. It is structurally similar to GABA and is reported in various research studies to increase GABA concentrations within the brain[1]. |
| SMILES | O=C(O)CC1(CN)CCCCC1.[H]Cl |
| 靶点 | Calcium Channel;GABAB receptor |
| 数据来源文献 | [1] J Pharmacol Exp Ther. 1999 Mar;288(3):1026-30; Br J Pharmacol. 2002 Jan;135(1):257-65. |
| 规格 | 50mg |
一种GABA类似物