阿维A
货号：
IA1810
品牌：
Jinpan
暂无详情
产品简介
| EC | EINECS 259-474-4 |
| MDL | MFCD00866632 |
| 别名 | 阿曲汀;维生素A酸;Ro 10-1670 |
| 英文名称 | Acitretin |
| CAS | 55079-83-9 |
| 分子式 | C21H26O3 |
| 分子量 | 326.43 |
| 纯度 | HPLC≥98% |
| 单位 | 瓶 |
| 生物活性 | Acitretin (Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis. Acitretin also can be used for the research of Alzheimer’s disease[1-[3]. |
| In Vitro | Acitretin (10 mg/kg; i.p. for 7 days) increases IL-6 in the central nervous system of Alzheimer’s disease model mice[3]. |
| SMILES | CC(/C=C/C(C(C)=CC(OC)=C1C)=C1C)=CC=CC(C)=CC(O)=O |
| 靶点 | Others |
| 数据来源文献 | [1]. Lee CS, et al. A review of acitretin, a systemic retinoid for the treatment of psoriasis. Expert Opin Pharmacother. 2005 Aug;6(10):1725-34.
[2]. Sengör B, et al. Effects of acitretin on spermatogenesis of rats. J Eur Acad Dermatol Venereol. 2006 Jul;20(6):689-92. [3]. Guilherme MDS, et, al. The Synthetic Retinoid Acitretin Increases IL-6 in the Central Nervous System of Alzheimer Disease Model Mice and Human Patients. Front Aging Neurosci. 2019 Jul 23;11:182 |
| 规格 | 50mg 250mg 500mg |
阿维A是一种新型、有效的第二代类维生素A，可用于银屑病的相关研究。