Tetramethylpyrazine；川芎嗪
货号：
IT0580
品牌：
Jinpan
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产品简介
| MDL | MFCD00006146 |
| EC | EINECS 214-391-2 |
| InChIKey | FINHMKGKINIASC-UHFFFAOYSA-N |
| InChI | InChI=1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3 |
| PubChem CID | 14296 |
| 别名 | 2,3,5,6-四甲基哌嗪;Chuanxingzine;Ligustrazine;2,3,5,6-Tetramethylpyrazine |
| 英文名称 | Tetramethylpyrazine |
| CAS | 1124-11-4 |
| 分子式 | C8H12N2 |
| 分子量 | 136.19 |
| 纯度 | HPLC≥98% |
| 单位 | 瓶 |
| 生物活性 | 川芎嗪已在中国广泛用于心脑血管疾病约40年。由于其在多系统中的有效性，尤其是在心血管方面。川芎嗪还被用于各种疾病，如冠心病，糖尿病，癌症和肝损伤。[1-3] |
| In Vivo | Tetramethylpyrazine 对大鼠具有潜在的抗神经和抗炎活性。 |
| SMILES | CC1=C(C)N=C(C)C(C)=N1 |
| 靶点 | Others |
| 数据来源文献 | [1]. Zhao Y, et al. Mechanisms and Clinical Application of Tetramethylpyrazine (an Interesting Natural Compound Isolated from Ligusticum Wallichii): Current Status and Perspective. Oxid Med Cell Longev. 2016;2016:2124638. [2]. Wu W, et al. Tetramethylpyrazine protects against scopolamine-induced memory impairments in rats by reversing the cAMP/PKA/CREB pathway. Behav Brain Res. 2013 Sep 15;253:212-6. [3]. Kao TK, et al. Tetramethylpyrazine reduces cellular inflammatory response following permanent focal cerebral ischemia in rats. Exp Neurol. 2013 Sep;247:188-201 |
| 规格 | 10mg 20mg 10mM*1mL in DMSO 50mg |
Tetramethylpyrazine是Ligusticum wallichii (Chuan Xiong)中的一种烷基吡嗪，具有多种生理活性。