GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat)

GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat)CAS号: 161748-29-4分子式: C140H214N36O43分子量: 3089.5描述来源序列纯度储存/保存方法别名外观

产品描述
描述
GLP-1 (9-36) is the result of the rapid degradation of GLP-1 (7-36)amide, by the enzyme dipeptidyl peptidase IV (DPP-4), which is widely expressed in a number of sites, including the endothelial cells of small gut arterioles. GLP-1 (9-36) accounts for the majority of GLP-1 that reaches the system circulation. Whereas GLP-1 (7-36) amide stimulates glucose-dependent insulin secretion and inhibits glucagon secretion, GLP-1(9-36)amide administration had no effect on glucose clearance or insulin secretion in humans. GLP-1(9-36)amide however was shown to exert cardioprotective actions in rodent hearts.
来源
synthesis
序列
H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
纯度
≥ 95%
储存/保存方法
-20°C,有效期2年。
基本信息
别名
EGTFTSDVSSYLEGQAAKEFIAWLVKGR – NH2
外观
White to off-white powder

分子结构图

GLP-1 (9-36) amide (human, bovine, guinea pig, mouse, porcine, rat)