FTI 277CAS号： 170006-73-2分子式： C22H29N3O3S2·C2HF3O2分子量： 561.64描述纯度储存/保存方法别名可溶性/溶解性靶点
| 产品描述 | |
| 描述 |
FTI 277 is an inhibitor that inhibits farnesyltransferase (FTase) (IC50 = 0.5 nM). Inhibits H-Ras and K-Ras processing in whole cells (IC50 values are 0.1 and 10 nM respectively) and disrupts constitutive H-Ras-specific actvation of MAPK. Causes significant antiproliferative effects in human malignant glioma cells and many other tumor cell lines. |
| 纯度 |
>98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
FTI-277,FTI277
|
| 可溶性/溶解性 |
Soluble in Water: ≥2 mg/mL
|
| 生物活性 | |
| 靶点 |
Farnesyl Transferase
|
分子结构图
