四烯雌酮
货号：
IA3910
品牌：
Jinpan
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产品简介
| MDL | MFCD00867855 |
| EC | EINECS 212-703-1 |
| 别名 | 烯丙基群勃龙; 硫酸金刚烷胺 |
| 英文名称 | Altrenogest |
| CAS | 850-52-2 |
| 分子式 | C21H26O2 |
| 分子量 | 310.43 |
| 储存条件 | -20℃ |
| 纯度 | ≥98% |
| 单位 | 瓶 |
| 生物活性 | Treatment of embryo-recipient mares with altrenogest appears to be beneficial in extending the degree of donor-recipient synchrony required for successful embryo transfer. Altrenogest treatment also seems to be conductive to pregnancy maintenance in recipients experiencing luteal dysfunction.[1] |
| In Vitro | Altrenogest (Allyltrenbolone) is a progestogen structurally related to veterinary steroid trenbolone. Treatment of embryo-recipient mares with Altrenogest (Allyltrenbolone) appears to be beneficial in extending the degree of donor-recipient synchrony required for successful embryo transfer[1]. The oil and gel Altrenogest (Allyltrenbolone) preparations are equally effective in modulating estrous behavior and time to estrus and ovulation. Altrenogest (Allyltrenbolone) treatment started late in diestrus appears to result in a high incidence of ovulation during treatment and when luteolysis and ovulation occur during treatment; the subsequent luteal phase is frequently prolonged due to failure of regression of the CL[2]. |
| SMILES | C[C@]([C@]1(O)CC=C)(C=C2)[C@](CC1)([H])[C@@](CC3)([H])C2=C(CC4)C3=CC4=O |
| 靶点 | Progesterone Receptor |
| 细胞实验 | The response to 15-d altrenogest treatment (Experiment 1) was characterized in 20 mares that were given 22 mg daily of altrenogest in oil (n = 10) or in gel (n = 10) from Day 10 to 25 after ovulation. [2] |
| 数据来源文献 | [1]. Parry-Weeks, L.C. and D.W. Holtan, Effect of altrenogest on pregnancy maintenance in unsynchronized equine embryo recipients. J Reprod Fertil Suppl, 1987. 35: p. 433-8. [2]. Daels, P.F., et al., Persistence of the luteal phase following ovulation during altrenogest treatment in mares. Theriogenology, 1996. 46(5): p. 799-811. |
| 规格 | 50mg 100mg |
是一种孕激素，结构与trenbolone相关，能作用于孕激素受体。