Rabbit anti-Antithrombin III Recombinant Monoclonal Antibody(294-303)别名宿主反应种属应用免疫原形式浓度纯化方法类型克隆号同种型储存/保存方法存储溶液背景说明UniProt
概述 | |
别名 |
ATIII
|
宿主 |
Rabbit
|
反应种属 |
Human
|
应用 |
Sandwich ELISA
|
免疫原 |
Recombinant protein
|
性能 | |
形式 |
Liquid
|
浓度 |
2 mg/mL
|
纯化方法 |
Protein A affinity column
|
类型 |
Monoclonal Antibody
|
克隆号 |
294-303
|
同种型 |
IgG
|
储存/保存方法 |
Store at 4℃ for one year.
|
存储溶液 |
PBS pH7.4, 0.03% Proclin 300
|
靶标 | |
背景说明 |
Antithrombin III (ATIII) is a nonvitamin K-dependent protease that inhibits coagulation by neutralizing the enzymatic activity of thrombin (factors IIa, IXa, Xa). Antithrombin III activity is markedly potentiated by heparin, the principal mechanism by which both heparin and low–molecular-weight heparin result in anticoagulation. Thrombin–antithrombin complex (TAT) is a protein complex of thrombin and antithrombin. It is a marker of net activation of coagulation. TAT is formed in response to the high thrombin level caused by coagulation following a ruptured vessel. Since thrombin is rapidly bound by antithrombin, TAT is a useful measure for thrombin level in the blood. Thrombin can pass the blood–brain barrier, destroying neurons and potentially causing cerebral edemas. The half-life of TAT is approximately 15 minutes.
|
UniProt |
P01008
|
实验结果图