Rabbit anti-Progesterone Receptor Monoclonal Antibody(JRMR-205)别名宿主反应种属应用纯化方法类型克隆号同种型储存/保存方法背景说明细胞定位UniProt
| 概述 | |
| 别名 |
Progesterone Receptor 抗体;NR3C3; PGR; PR
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human, Mouse
|
| 应用 |
IHC-P:1:200-1:1000;
|
| 性能 | |
| 纯化方法 |
Protein A
|
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
JRMR-205
|
| 同种型 |
IgG
|
| 储存/保存方法 |
储存温度：-20℃，避免反复冻融
|
| 靶标 | |
| 背景说明 |
类固醇激素及其受体参与调控真核生物基因表达，影响靶组织的细胞增殖和分化。根据异构体的不同，孕激素受体起转录激活或抑制的作用。
|
| 细胞定位 |
细胞核
|
| UniProt |
P06401
|
Rabbit anti-ZNF300 Polyclonal Antibody别名宿主特异性反应种属预测反应种属应用分子量免疫原浓度纯化方法类型同种型储存/保存方法存储溶液研究领域背景说明细胞定位UniProt
| 概述 | |
| 别名 |
ZNF300抗体;Kruppel like zinc finger protein; Zinc finger protein 300; ZN300_HUMAN
|
| 宿主 |
Rabbit
|
| 特异性 |
ZNF300
|
| 反应种属 |
Mouse
|
| 预测反应种属 |
Human;
|
| 应用 |
WB=1:500-2000 ELISA=1:500-1000
|
| 分子量 |
Predicted molecular weight: 68kDa
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 |
KLH conjugated synthetic peptide derived from human ZNF300:165-250/604
|
| 性能 | |
| 浓度 |
1mg/ml
|
| 纯化方法 |
affinity purified by Protein A
|
| 类型 |
Polyclonal Antibody
|
| 同种型 |
IgG
|
| 储存/保存方法 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
|
| 存储溶液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
|
| 研究领域 |
染色质和核信号 信号转导 转录调节因子
|
| 靶标 | |
| 背景说明 |
ZNF300 contains C2H2 (or Kruppel)-type zinc finger motifs that tetrahedrally coordinate zinc ions and form a protein structure that can bind DNA and regulate transcription (Gou et al.,2004 [PubMed 14746915]). ZNF300 belongs to the krueppel C2H2 type zinc finger protein family. It contains twelve C2H2 type zinc fingers and one KRAB domain. ZNF300 has a transcriptional repressor activity. Expressed mostly in heart, skeletal muscle and brain. Isoforms 1 and 2 are highly expressed in testis. There are three named isoforms.
|
| 细胞定位 |
细胞核
|
| UniProt |
Q96RE9
|
实验结果图
Sample:
Lane1: Testis (Mouse) Lysate at 30 ug
Lane2: Small intestine (Mouse) Lysate at 30 ug
Primary: Anti-ZNF300(JP120084a) at 1:200 dilution;
Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1:3000 dilution;
Predicted band size : 66kD
Observed band size : 70,66kD
Rabbit anti-CD42b Monoclonal Antibody(JRMR-224)别名宿主反应种属应用分子量纯化方法类型克隆号同种型储存/保存方法背景说明细胞定位UniProt
| 概述 | |
| 别名 |
CD42b 抗体;GP1BA; GP-Ib alpha; GPIbA;
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human, Mouse
|
| 应用 |
WB:1:2000; IHC-P:1:200-1:1000;
|
| 分子量 |
Predicted molecular weight: 72kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 纯化方法 |
Protein A
|
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
JRMR-224
|
| 同种型 |
IgG
|
| 储存/保存方法 |
储存温度：-20℃，避免反复冻融
|
| 靶标 | |
| 背景说明 |
GP-Ib是血小板的一种表面膜蛋白，通过与已经结合到内皮下层的vWF的A1域结合而参与血小板栓塞的形成。
|
| 细胞定位 |
膜
|
| UniProt |
P07359
|
Rabbit anti-sFlt-1/VEGF Receptor 1 Recombinant Monoclonal Antibody(233-29)别名宿主反应种属应用免疫原形式浓度纯化方法类型克隆号储存/保存方法存储溶液背景说明细胞定位UniProt
| 概述 | |
| 别名 |
VEGFR-1, FRT
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human
|
| 应用 |
IHC-P: 1:1000
|
| 免疫原 |
Recombinant protein
|
| 性能 | |
| 形式 |
Liquid
|
| 浓度 |
0.25 mg/mL
|
| 纯化方法 |
Protein A affinity column
|
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
233-29
|
| 储存/保存方法 |
Store at -20℃ for one year.
|
| 存储溶液 |
PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
|
| 靶标 | |
| 背景说明 |
Vascular endothelial growth factor (VEGF) represents a growth factor with important pro-angiogenic activity, having a mitogenic and an anti-apoptotic effect on endothelial cells, increasing the vascular permeability, promoting cell migration, etc. VEGF binds to tyrosine kinase cell receptors (VEGFRs): VEGFR-1 [Fms-like tyrosine kinase 1 (Flt-1)], VEGFR-2 [kinase insert domain receptor (KDR) in human; fetal liver kinase 1 (Flk-1) in mouse] and VEGFR-3 [Fms-like tyrosine kinase 4 (Flt-4)]. While VEGFR-1 and VEGFR-2 are expressed predominantly on vascular endothelial cells, VEGFR-3 is expressed especially on lymphatic endothelial cells [PMID: 30173249].
|
| 细胞定位 |
Secreted
|
| UniProt |
P17948-2
|
实验结果图
IHC shows positive staining in paraffin-embedded human placenta. Anti-sFlt-1/VEGF Receptor 1 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human tonsil. Anti-sFlt-1/VEGF Receptor 1 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human breast cancer. Anti-sFlt-1/VEGF Receptor 1 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
IHC shows positive staining in paraffin-embedded human endometrial cancer. Anti-sFlt-1/VEGF Receptor 1 antibody was used at 1/1000 dilution, followed by a HRP Polymer for Mouse & Rabbit IgG (ready to use). Counterstained with hematoxylin. Heat mediated antigen retrieval with Tris/EDTA buffer pH9.0 was performed before commencing with IHC staining protocol.
2ACE,Rabbit IgG anti-Mouse/Rat/Human,WB/IP/
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Rabbit anti-GSK3α/β(pY279/216) Polyclonal Antibody描述别名宿主特异性反应种属应用分子量免疫原纯化方法类型储存/保存方法UniProt
| 概述 | |
| 描述 |
Rabbit polyclonal antibody to GSK3 alpha/beta (pY279/216)
|
| 别名 |
GSK3 alpha抗体, beta抗体;GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B
|
| 宿主 |
Rabbit
|
| 特异性 |
Recognizes endogenous levels of GSK3 alpha/beta (pY279/216) protein.
|
| 反应种属 |
Human, Mouse, Rat, Zebrafish
|
| 应用 |
WB 1:500 – 1:1000, IHC 1:50 – 1:200
|
| 分子量 |
Detects a band of approximately 51/46kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 免疫原 |
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human GSK3 alpha/beta (pY279/216). The exact sequence is proprietary.
|
| 性能 | |
| 纯化方法 |
The antibody was purified by immunogen affinity chromatography.
|
| 类型 |
Polyclonal Antibody
|
| 储存/保存方法 |
Shipped at 4°C. Upon delivery aliquot and store at -20°C for one year. Avoid freeze/thaw cycles.
|
| 靶标 | |
| UniProt |
P49840
|
实验结果图
Western blot analysis of GSK3 alpha/beta (pY279/216) expression in mouse testis (A), rat testis (B), rat spleen (C) whole cell lysates.
Immunohistochemical analysis of GSK3 alpha/beta (pY279/216) staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Rabbit anti-PAP Monoclonal Antibody(JRMR-267)描述别名宿主反应种属应用分子量形式纯化方法类型克隆号同种型储存/保存方法细胞定位UniProt
| 概述 | |
| 描述 |
一种非特异性酪氨酸磷酸酶，在酸性条件下（pH4-6）使多种底物去磷酸化，包括烷基、芳基和酰基正磷酸单酯和磷酸化蛋白质。
|
| 别名 |
PAP 抗体;ACPP; ACP3
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human
|
| 应用 |
WB:1:500-1:1000,IHC-P:1:50-1:100,FC:1:50-1:100
|
| 分子量 |
Predicted molecular weight: 45kD
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| 性能 | |
| 形式 |
液态
|
| 纯化方法 |
Protein A
|
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
JRMR-267
|
| 同种型 |
IgG
|
| 储存/保存方法 |
储存温度：-20℃，避免反复冻融
|
| 靶标 | |
| 细胞定位 |
分泌，溶酶体膜
|
| UniProt |
P15309
|
2KAP79,Rabbit IgG anti-Human,WB/IP/
|
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Rabbit anti-VISTA Monoclonal Antibody(JRMR-283)别名宿主反应种属应用纯化方法类型克隆号同种型储存/保存方法背景说明细胞定位UniProt
| 概述 | |
| 别名 |
VISTA 抗体;C10orf54; SISP1; VSIR; Sisp-1; Platelet receptor Gi24
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human
|
| 应用 |
IHC-P:1:100-1:1000;
|
| 性能 | |
| 纯化方法 |
Protein A
|
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
JRMR-283
|
| 同种型 |
IgG
|
| 储存/保存方法 |
储存温度：-20℃，避免反复冻融
|
| 靶标 | |
| 背景说明 |
VSIR（V-Set免疫调节受体）是一种蛋白质编码基因。与VSIR相关的疾病包括鱼鳞病，先天性，常染色体隐性遗传6和Monckeberg动脉硬化。其相关途径包括细胞粘附分子（CAM）和NF-κB信号传导。该基因的重要旁系同源物是VSIG8。
|
| 细胞定位 |
膜
|
| UniProt |
Q9H7M9
|
Rabbit anti-t-PA Recombinant Monoclonal Antibody(215-4)别名宿主反应种属应用免疫原形式浓度纯化方法类型克隆号储存/保存方法存储溶液背景说明UniProt
| 概述 | |
| 别名 |
Tissue-type plasminogen activator; t-plasminogen activator; tPA
|
| 宿主 |
Rabbit
|
| 反应种属 |
Human
|
| 应用 |
Sandwich ELISA
|
| 免疫原 |
Recombinant protein
|
| 性能 | |
| 形式 |
Liquid
|
| 浓度 |
2 mg/ml
|
| 纯化方法 |
Protein A affinity column
|
| 类型 |
Monoclonal Antibody
|
| 克隆号 |
215-4
|
| 储存/保存方法 |
Store at 2 to 8℃ for one year.
|
| 存储溶液 |
PBS, pH 7.4, 0.03% Proclin 300
|
| 靶标 | |
| 背景说明 |
Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown. Human tPA has a molecular weight of ~70 kDa in the single-chain form. tPA can be manufactured using recombinant biotechnology techniques; tPA produced by such means are referred to as recombinant tissue plasminogen activator (rtPA). Specific rtPAs include alteplase, reteplase, and tenecteplase. They are used in clinical medicine to treat embolic or thrombotic stroke. The use of this protein is contraindicated in hemorrhagic stroke and head trauma. The antidote for tPA in case of toxicity is aminocaproic acid. Increased levels of PAI-1 and tPA are associated with increased risk of cardiovascular disease, especially in patients with concomitant insulin resistance. It has been suggested that the tPA/PAI-1 complex would be an even stronger marker for thrombotic events than tPA antigen, and increased levels of tPA/PAI-1 complex were indeed recently shown to predict increased risk for first-ever stroke.
|
| UniProt |
P00750
|
实验结果图
配对表格