Rabbit anti-CD217 Polyclonal Antibody别名宿主特异性反应种属预测反应种属应用分子量免疫原浓度纯化方法类型同种型储存/保存方法存储溶液研究领域背景说明细胞定位UniProt
| 概述 | |
| 别名 |
IL17RA抗体, CD217抗体;IL-17RA; IL17A Receptor; Interleukin-17 receptor A; IL17RA; CDw217; hIL-17R; IL-17R; MGC10262; IL-17 receptor A; CD217; IL17 RECEPTOR; IL17FR; AW538159; I17RA_HUMAN
|
| 宿主 |
Rabbit
|
| 特异性 |
IL17A Receptor
|
| 反应种属 |
Mouse
|
| 预测反应种属 |
Human;Rat;
|
| 应用 |
ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
|
| 分子量 |
Predicted molecular weight: 92kDa
|
| 免疫原 |
KLH conjugated synthetic peptide derived from human IL-17R:201-300/866
|
| 性能 | |
| 浓度 |
1mg/ml
|
| 纯化方法 |
affinity purified by Protein A
|
| 类型 |
Polyclonal Antibody
|
| 同种型 |
IgG
|
| 储存/保存方法 |
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
|
| 存储溶液 |
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
|
| 研究领域 |
细胞膜受体 细胞表面分子
|
| 靶标 | |
| 背景说明 |
Interleukin 17A (IL17A)is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. [provided by RefSeq]
|
| 细胞定位 |
细胞膜 分泌型蛋白
|
| UniProt |
Q96F46
|
实验结果图
Paraformaldehyde-fixed, paraffin embedded (Mouse brain); Antigen retrieval by boiling in sodium citrate buffer for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer at 37°C for 30min; Antibody incubation with (IL17A Receptor) Polyclonal Antibody, Unconjugated secondary primary antibody at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.