Recombinant human CBX2 protein
货号：
P03733
品牌：
Jinpan
产品简介
| 基因名 | CBX2 |
| 英文全称 | chromobox homolog 2 (Pc class homolog, Drosophila) |
| 别称 | CDCA6;M33;SRXY5 |
| 中文名称 | chromobox蛋白同源蛋白2 |
| Uniprot | Q14781 |
| GeneID | 84733 |
| 交叉反应(推测) | Human Mouse |
| 氨基酸大小 | 23kDa |
| 表达氨基酸 | 1-212aa |
| Background | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development.PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ‘Lys-119’, rendering chromatin heritably changed in its expressibility.Binds to histone H3 trimethylated at ‘Lys-9’ (H3K9me3) or at ‘Lys-27’ (H3K27me3) .Plays a role in the lineage differentiation of the germ layers in embryonic development.Involved in sexual development, acting as activator of NR5A1 expression. |
| Application | Immunology research |
| Derived from | E.coli |
| Purification | NI-NTA affinity purification |
| Formulation | Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0. |
| Shipping | The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below. |
| Storage | Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years. |
| Reconstitution | Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Purity | Purity≥85% as determined by reducing SDS-PAGE. |
| Endotoxin | / |
| Bioactive | Unknown. (Ban’t be used in biological activity experiments such as cell culture, treatment and diagnosis.) |
| 规格 | 10ug 50ug 100ug 1mg |