AKOS037652256

AKOS037652256CAS号: 2171065-77-1分子式: C24H26ClFN4O4S2分子量: 553.07描述纯度储存/保存方法靶点In vitro(体外研究)

产品描述
描述
AKOS037652256 can be used as a TRPML modulator for the treatment of diseases associated with TRPML activity such as lysosomal accumulation disorders, muscular dystrophy, common age-related neurodegenerative diseases, oxidative stress or reactive oxygen species (ROS)-related diseases and ageing.
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
生物活性
靶点
TRPML:< = 2 µM(AC50), TRPML1:< = 2 µM(AC50)
In vitro(体外研究)
AKOS037652256 (Compound 8) (0.1-3 μM) was sufficient to induce TFEB-nuclear translocation (nuclear to cytosol ratio increased in a dose-dependent manner.[2]

AKOS025692697

AKOS025692697CAS号: 1606572-10-4分子式: C19H23ClF3N3O3S分子量: 465.917描述储存/保存方法可溶性/溶解性

产品描述
描述
AKOS025692697 is a biochemical.
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:60 mg/ml (128.78 mM)