ONO-7300243
| 有效期 | 2年 |
| MDL | MFCD30534399 |
| 别名 | 2-(4-((3,5-二甲氧基-4-甲基-N-(3-苯基丙基)苯甲酰胺)甲基)苯基)乙酸 |
| 英文名称 | ONO-7300243 |
| CAS | 638132-34-0 |
| 分子式 | C28H31NO5 |
| 分子量 | 461.55 |
| 储存条件 | -20°C |
| 纯度 | ≥98% |
| 外观（性状） | White Powder |
| 单位 | 瓶 |
| SMILES | O=C(O)CC1=CC=C(CN(C(C2=CC(OC)=C(C)C(OC)=C2)=O)CCCC3=CC=CC=C3)C=C1 |
| 靶点 | LPL Receptor（LPA1） |
| 规格 | 5mg 10mg |
ONO-AE3-208CAS号： 402473-54-5分子式： C24H21FN2O3分子量： 404.4335描述纯度储存/保存方法别名外观靶点In vivo(体内研究)
| 产品描述 | |
| 描述 |
ONO-AE3-208(AE 3-208) is an EP4 antagonist; suppresses cell invasion, migration, and metastasis of prostate cancer.
|
| 纯度 |
>98%
|
| 储存/保存方法 |
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
|
| 基本信息 | |
| 别名 |
AE 3-208;ONO AE3 208
|
| 外观 |
Powder
|
| 生物活性 | |
| 靶点 |
Prostaglandin Receptor
|
| In vivo(体内研究) |
ONO-AE3-208 surpresses the in vivo bone metastasis of PC3 cells in mice. The photon tumor burdens are significantly increased in a time-dependent manner in the control group in comparison with those in the ONO-AE3-208-treated group. The rate of metastasis formation is significantly higher in the former than in the latter. The median time of metastasis formation is 29 d in the ONO-AE3-208-treated animals as compared with 21 d in the controls.
|
分子结构图
ONO-4059 analogue
| 别名 | ONO-WG-307 |
| CAS | 1351635-67-0 |
| 分子式 | C25H24N6O3 |
| 分子量 | 456.5 |
| 储存条件 | -20℃ |
| 纯度 | ≥98% |
| 单位 | 瓶 |
| SMILES | O=C1N([C@H]2CCCN(C(C=C)=O)C2)C3=NC=NC(N)=C3N1C4=CC=C(OC5=CC=CC=C5)C=C4 |
| 靶点 | Btk |
| 规格 | 5mg 10mg 25mg |