三磷酸腺苷二钠,Adenosine-5'-triphosphate disodium salt hydrate,CAS:987-65-5,货号:A8270-1g
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品牌: | solarbio | |
规格: | 1g |
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三磷酸腺苷二钠,Adenosine-5'-triphosphate disodium salt hydrate,CAS:987-65-5,货号:A8270-1g
市场价: | ¥50.0 | |
价格: |
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品牌: | solarbio | |
规格: | 1g |
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cAMP;环磷酸腺苷
EC | EINECS 200-492-9 |
MDL | MFCD00005845 |
别名 | 环化腺苷酸; 3,5-环磷酸腺苷; Adenosine Cyclophosphate; Adenosine 3′,5′-cyclicmonophosphoric acid; Adenosine 3′,5′-cyclophosphate |
英文名称 | cAMP |
CAS | 60-92-4 |
分子式 | C10H12N5O6P |
分子量 | 329.21 |
纯度 | HPLC≥98% |
单位 | 瓶 |
SMILES | NC1=C2N=CN([C@@H]3O[C@]4([H])COP(O)(O[C@@]4([H])[C@H]3O)=O)C2=NC=N1 |
靶点 | Endogenous Metabolite |
规格 | 50mg 10mM*1mL in Water 100mg |
是有丝分裂信使,在细胞周期中能够促进 G1 期到 S 期的过程。
Adenosine 5′-triphosphate disodium saltCAS号: 987-65-5分子式: C10H14N5O13P3.2Na分子量: 551.14描述纯度储存/保存方法别名外观可溶性/溶解性靶点In vitro(体外研究)In vivo(体内研究)
产品描述 | |
描述 |
Adenosine 5′-triphosphate disodium salt is a P2 purinoceptor agonist. |
纯度 |
>98%
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储存/保存方法 |
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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基本信息 | |
别名 |
三磷酸腺苷二钠;腺苷-5′-三磷酸二钠盐;ATP disodium salt
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外观 |
White crystalline powder
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可溶性/溶解性 |
water : 100 mg/mL (181.44 mM; Need ultrasonic)
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生物活性 | |
靶点 |
P2X Receptor
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In vitro(体外研究) |
ATP release and autocrine feedback through P2Y2 and A3 receptors provide signal amplification, controlling gradient sensing and migration of neutrophils. ATP results in production of reactive oxygen species (ROS), which stimulates the phosphatidylinositol 3-kinase (PI3K) pathway and subsequent Akt and ERK1/2 activation. ATP-dependent ROS production and PI3K activation also stimulate transcription of genes required for an oxidative stress response. ATP-mediated ROS-dependent PI3K is required for activation of caspase-1 and secretion of IL-1beta and IL-18. ATP potently stimulates TNF-alpha release, resulting from TNF-alpha mRNA expression in rat cultured brain microglia. ATP-induced TNF-alpha release is Ca(2+)-dependent, and a sustained Ca(2+) influx correlated with the TNF-alpha release in ATP-stimulated microglia. ATP-induced TNF-alpha release is inhibited by PD 098059, an inhibitor of extracellular signal-regulated protein kinase (ERK) kinase 1 (MEK1), which activates ERK, and also by SB 203580, an inhibitor of p38 mitogen-activated protein kinase. ATP rapidly activates both ERK and p38 even in the JPence of extracellular Ca(2+). ATP-induced cytotoxicity is mediated by classical alterations of apoptosis, including membrane blebbing, nuclear condensation, and DNA fragmentation. ATP but not other nucleotides lead to the potent and selective activation of NF-κB in microglial cells through a P2Z receptor-mediated pathway.
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In vivo(体内研究) |
ATP regulates microglial branch dynamics in the intact mice brain, and its release from the damaged tissue and surrounding astrocytes mediates a rapid microglial response towards injury.
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分子结构图
腺苷,Adenosine,CAS:58-61-7,货号:A8240-5g
市场价: | ¥130.0 | |
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品牌: | solarbio | |
规格: | 5g |
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三磷酸腺苷二钠,Adenosine-5'-triphosphate disodium salt hydrate,CAS:987-65-5,货号:A8270-5g
市场价: | ¥150.0 | |
价格: |
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品牌: | solarbio | |
规格: | 5g |
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三磷酸腺苷二钠,Adenosine-5'-triphosphate disodium salt hydrate,CAS:987-65-5,货号:A8270-25g
市场价: | ¥700.0 | |
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品牌: | solarbio | |
规格: | 25g |
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腺苷-5'-二磷酸二钠盐,Adenosine-5'-diphosphate disodium salt,CAS:16178-48-6,货号:A8290-500mg
市场价: | ¥160.0 | |
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品牌: | solarbio | |
规格: | 500mg |
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腺苷-5'-二磷酸二钠盐,Adenosine-5'-diphosphate disodium salt,CAS:16178-48-6,货号:A8290-1g
市场价: | ¥240.0 | |
价格: |
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品牌: | solarbio | |
规格: | 1g |
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Adenosine 腺苷 标准品
EC | EINECS 200-389-9 |
MDL | MFCD00005752 |
别名 | 腺甙;腺嘌呤核苷;D-腺嘌呤核苷;腺呤配糖;腺尿环核苷 |
英文名称 | Adenosine |
CAS | 58-61-7 |
分子式 | C10H13N5O4 |
分子量 | 267.24 |
储存条件 | 2-8°C,密封,遮光。 |
纯度 | HPLC≥98% |
外观(性状) | 白色结晶粉末。 |
单位 | 瓶 |
SMILES | NC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](CO)O3)C=N2)=NC=N1 |
规格 | 20mg |
用途:用于含量测定/鉴定/药理实验等。
溶解性:可溶于碱、DMSO
熔点:234-235℃
旋光度:-61.7 (c=0.7 in H2O)
用法 :色谱条件:以磷酸盐缓冲液(pH6.5)[取0.01mol/L磷酸二氢钠68.5mL与0.01mol/L磷酸氢二钠31.5mL,混合(pH6.5)]~甲醇(85:15)为流动相;检测波长为260nm。(仅供参考)
腺苷-5′-三磷酸 标准品
EC | EINECS 200-283-2 |
MDL | MFCD00150755 |
别名 | 三磷腺苷;ATP;Adenosine triphosphate; |
英文名称 | Adenosine Triphosphate |
CAS | 56-65-5 |
分子式 | C10H16N5O13P3 |
分子量 | 507.18 |
储存条件 | -20℃ |
纯度 | HPLC≥98% |
外观(性状) | Off-white Powder |
单位 | 瓶 |
SMILES | O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COP(O)(OP(OP(O)(O)=O)(O)=O)=O |
规格 | 20mg |