AG-270 is an allosteric and orally active inhibitor of MAT2A.
纯度
98%
储存/保存方法
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
基本信息
可溶性/溶解性
DMSO:6 mg/mL (12.26 mM)
生物活性
靶点
Mat2A:14 nM
In vitro(体外研究)
AG-270 exhibits an IC50 of 20 nM in HCT116 MTAP-null cell SAM at 72 h[1].AG-270 demonstrates potent reduction in levels of intracellular SAM, as well as MTAP-null–selective antiproliferative activity in the HCT116 MTAP isogenic cell model in vitro[1].
提供产品:致力于为中国干细胞领域的干细胞科学研究、脐带血/造血干细胞/脐带/脂肪/胎盘干细胞库、干细胞临床转化医学、干细胞美容及干细胞抗衰老、免疫细胞治疗、T细胞治疗、临床干细胞治疗等再生医学和个体化治疗产业链的相关客户提供:MSC间充质干细胞培养基、iPS/ES胚胎干细胞培养基、血清替代物、羊水培养基、基底膜基质胶细胞支架、干细胞生长分化调控因子、BioMarker 流式检测抗体、支原体检测试剂盒、内毒素检测试剂盒、干细胞存储细胞冻存袋、细胞培养瓶、USP级DMSO二甲基亚砜细胞冻存液、细胞培养相关试剂耗材仪器等种类丰富的产品,以“Focus on improving the quality of Stem Cells专注干细胞研究,提升干细胞品质”为己任,我们与客户携手为中国干细胞产业的发展而前行。
● BEBM™Basal Medium 500ml ● BPE, 2.0 ml ● Hydrocortisone, 0.5 ml ● hEGF, 0.5 ml ● Epinephrine, 0.5ml ● Insulin,0.5 ml ● Transferrin, 0.5 ml ● Triiodothyronine, 0.5 ml ● Retinoic Acid, 0.5 ml ● GA, 0.5ml
英文简述:
Clonetics™ Media Products are specially designed to support the growth of human and animal primary derived cells. Media systems have been specifically developed and optimized for various cell systems. BEGM™ BulletKit™ is serum free and has been optimized to grow diseased and normal bronchial epithelial cells.
Media are supplied in several formats:
• Basal Medium – contains no growth factors, cytokines, or supplements • SingleQuots™ Kit – growth factors, cytokines, and supplements • BulletKits™ – basal medium and SingleQuots™ Kit packaged together