NT-010/050/250-NT-3 神经生长因子 StemRD NT-010/050/250-细胞因子蛋白添加物

产品名称:NT-3 神经生长因子
产品编号:NT-010/050/250
品牌;StemRD
厂家:StemRD
产品规格:10/50/250ug
储存条件:-80℃
到货时间:2-5天

产品信息

Neurotrophin-3 (NT-3) is a member of the NGF family of neurotrophic factors that also include NGF, BDNF and NT-4/5. These secreted neurotrophins are processed proteolytically from a disulfide-containing precursor. The mature and bio-active form of NT-3 is a noncovalentlylinked homodimer of two 13.6kDa identical subunits. StemRD's NT-3is made in human 293 cells which renders natural dimerization and human-specific post-translational modifications. We purified this product through a series of chromatography including HPLC to near homogeneity.

Purity:
Greater than 95% by SDS-PAGE under reducing conditions and visualized by silver staining.

Biological Activity
The activity was determined by using a NFAT luciferase reporter gene assay in 293 cells cotransfected with TrkC receptor (Wang, et al., Cellular Assays for High-Throughput Screening for Modulators of Trk Receptor Tyrosine Kinases. Curr Chem Genomics. 2008; 1: 27–33). The EC50 ranges from0.5 – 5.0 ng/ml

Amuvatinib/MP470

Amuvatinib/MP470

货号:
IA1860

品牌:
Jinpan

Amuvatinib/MP470

暂无详情
产品简介
别名 N-(1,3-苯并二氧戊环-5-基甲基)-4-苯并呋喃并[3,2-D]嘧啶-4-基-1-哌嗪硫代甲酰胺;MP470
英文名称 Amuvatinib/MP470
CAS 850879-09-3
分子式 C23H21N5O3S
分子量 447.51
纯度 ≥98%
单位
SMILES S=C(N1CCN(C2=C3OC4=CC=CC=C4C3=NC=N2)CC1)NCC5=CC=C6OCOC6=C5
靶点 FLT3;PDGFR��;c-Kit
规格 2mg 10mg 20mg
Amuvatinib是多靶点抑制剂。

天然免疫学热点领域科研抗体(AbD Serotec®)—细胞增殖标志物抗体

天然免疫学热点领域科研抗体(AbD Serotec®)—细胞增殖标志物抗体

AbD Serotec公司生产的Rat anti Brdu, clone BU1/75(ICR1), 能够识别游离的以及和单链DNA结合的Brdu, 是目前文献引用最多的anti-Brdu抗体, 同时AbD Serotec是该抗体唯一的商品化生产商。

 

Ki-67是一种增殖细胞相关的核抗原, 不表达于静止期的细胞, Ki-67的反义寡核苷酸能够抑制细胞的增殖, 揭示Ki-67蛋白对细胞增殖是绝对必需的。

福尔马林固定, 石蜡包埋的小鼠结肠组织切片,          MCF-7细胞的anti Ki-67免疫荧光染色结果
Rat anti Brdu(MCA2060)染色结果                             (HCA006, 绿色), Phalloidin(红色)和Hoechst
                                                                                         (蓝色)复染。

AbD Serotec公司提供的最受欢迎的细胞增殖标志物抗体

 产品编号  抗体类型  特异性  克隆号  宿主  适用种属  形式  规格  应用
 MCA2060  mAb  BrdU  BU1/75
 (ICR1)
 Rat  Purified  0.2 mg  F*, IF, P*
 MCA2060GA  mAb  BrdU  BU1/75
 (ICR1)
 Rat  Purified  0.1 mg  F*, IF, P*
 MCA2060T  mAb  BrdU  BU1/75  (ICR1)  Rat  Purified  20 μg  F*, IF, P*
MCA2060A488 mAb BrdU BU1/75 (ICR1) Rat ALEXA FLUOR® 488 100 TESTS/1ml F*
MCA2060B mAb BrdU BU1/75 (ICR1) Rat Biotin 0.1 mg F*
MCA2060F mAb BrdU BU1/75 (ICR1) Rat FITC 0.1 mg F*
MCA2060FT mAb BrdU BU1/75 (ICR1) Rat FITC 0.25 mg F*
MCA2060P mAb BrdU BU1/75 (ICR1) Rat HRP 0.5 mg E, P*
MCA2060PA mAb BrdU BU1/75 (ICR1) Rat HRP 0.1 mg E, P*
MCA2483 mAb BrdU Bu20a Mouse Purified 0.2 mg C, F*, P*
MCA2483FA mAb BrdU Bu20a Mouse FITC 50 μg F*
MCA2483T mAb BrdU Bu20a Mouse Purified 20 μg C, F*, P*
HCA006 mAb Ki-67 2531 (Fab) HuCAL® Human, Bovine, Dog Purified 0.1 mg C, E, IF, P*,WB
HCA053 mAb Ki-67 2531 HuCAL® Human, Bovine, Dog Purified 0.1 mg C, E, P*, WB
MAb mAb Ki-67 2531 HuCAL® Human, Bovine,Dog Purified 50 μg C, E, P*, WB
HCA117 mAb Ki-67 2815 HuCAL® Human Purified 0.1 mg E, P*
HCA117A mAb Ki-67 2815 HuCAL® Human Purified 50 μg E, P*
MCA289 mAb Ki-67 Ki67 Mouse Human Supernatant 2 ml C*, F*, IF
MCA289T mAb Ki-67 Ki67 Mouse Human Supernatant 0.2 ml C*, F*, IF
MCA1859 mAb MCM2 CRCT2.1 Mouse Human Purified 0.1 mg C, P*, WB
AHP1419 pAb PCNA Rabbit Broad Purified 50 μg E, P*, WB
MCA1558 mAb PCNA PC10 Mouse Broad Purified 0.1 mg C, F*, IP, P,WB
MCA1558F mAb PCNA PC10 Mouse Broad FITC 0.1 mg F*
MCA1558H mAb PCNA PC10 Mouse Broad Purified  6 ml C, P
MCA3328Z mAb PCNA 1G7 Mouse Human Azide Free 0.1 mg IF, WB

AbD serotec公司Brdu抗体参考文献
1.     Vanderlaan, M. & Thomas, C.B. (1985) Characterization of monoclonal antibodies to bromodeoxyuridine.Cytometry. 6: 501-505.
2.     Ghiringelli, F. et al. (2005) Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation.J. Exp. Med. 202: 919-929.
3.     Dolbeare, F. (1995) Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part I: Historical perspectives, histochemical methods and cell kinetics.Histochem. J. 27: 339-369.
4.     Micheli, L. et al. (2010) PC4/Tis7/IFRD1 stimulates skeletal muscle regeneration and is involved in myoblast differentiation as a regulator of MyoD and NF-kB.J Biol Chem. Dec 14. [Epub ahead of print]
5.     Das, G. et al. (2009) Cyclin D1 fine-tunes the neurogenic output of embryonic retinal progenitor cells.Neural Dev. 4: 15.
6.     Nakhai, H. et al. (2008) Conditional ablation of Notch signaling in pancreatic development.Development. 135: 2757-65.
7.     Ghai, K. et al. (2010) Notch signaling influences neuroprotective and proliferative properties of mature Müller glia. 
J Neurosci. 30: 3101-12.
8.     Kim, T.H. et al. (2011) Genetic evidence that intestinal notch functions vary regionally and operate through a common mechanism of math1 repression.J Biol Chem. Jan 31. [Epub ahead of print]
9.     Sabo, J.K. et al. (2011) Remyelination is altered by bone morphogenic protein signaling in demyelinated lesions.
J Neurosci. 31: 4504-10.
10.   Bourgo, R.J. et al. (2011) RB deletion disrupts coordination between DNA replication licensing and mitotic entry in vivo.Mol Biol Cell. 22: 931-9.
11.   Bugler, B. et al. (2010) Unscheduled expression of CDC25B in S-phase leads to replicative stress and DNA damage.
Mol Cancer. 9: 29.
12.   Caronia, G. et al. (2010) Bone morphogenetic protein signaling in the developing telencephalon controls formation of the hippocampal dentate gyrus and modifies fear-related behavior.J Neurosci. 30: 6291-301.
13.   Xu, Q. et al. (2010) Sonic hedgehog signaling confers ventral telencephalic progenitors with distinct cortical interneuron fates.Neuron. 65: 328-40.
14.   Puverel, S. et al. (2011) RanBPM is essential for mouse spermatogenesis and oogenesis.Development. 138: 2511-21.
15.   Amador-Arjona, A. et al. (2011) Primary cilia regulate proliferation of amplifying progenitors in adult hippocampus: implications for learning and memory.J Neurosci. 31: 9933-44.
16.   Chojnacki, A. et al. (2011) PDGFR{alpha} Expression Distinguishes GFAP-Expressing Neural Stem Cells from PDGF-Responsive Neural Precursors in the Adult Periventricular Area.J Neurosci. 31: 9503-12.
17.   Kroehne, V. et al. (2011) Regeneration of the adult zebrafish brain from neurogenic radial glia-type progenitors.
Development. 138: 4831-41.
18.   Bonzo, J.A. et al. (2012) Suppression of Hepatocyte Proliferation by Hepatocyte Nuclear Factor 4a in Adult Mice.
J Biol Chem. Jan 12. [Epub ahead of print]
19.   Liu, M.T. et al. (2009) 5-HT4 receptor-mediated neuroprotection and neurogenesis in the enteric nervous system of adult mice.J Neurosci. 29: 9683-99.
20.   Lundgren, O. et al. (2011) Intestinal epithelial stem/progenitor cells are controlled by mucosal afferent nerves.
PLoS One. 6: e16295.
21.   Knopf, F. et al. (2011) Bone regenerates via dedifferentiation of osteoblasts in the zebrafish fin.Dev Cell. 20: 713-24.
22.   Contet, C. et al. (2013) µ-Opioid receptors mediate the effects of chronic ethanol binge drinking on the hippocampal neurogenic niche.Addict Biol. Mar 6. [Epub ahead of print]
23.   Grotek, B. et al. (2013) Notch signaling coordinates cellular proliferation with differentiation during zebrafish fin regeneration.Development. 140: 1412-23.
24.   Lee, N. et al. (2013) Ciliary neurotrophic factor receptor regulation of adult forebrain neurogenesis.
J Neurosci. 33: 1241-58.
25.   Wang, W. et al. (2013) Extracellular signal-regulated kinase 5 (ERK5) mediates prolactin-stimulated adult neurogenesis in the subventricular zone and olfactory bulb.J Biol Chem. 288: 2623-31
26.   Zemans, R.L. et al. (2013) Role of ß-catenin-Regulated CCN Matricellular Proteins in Epithelial Repair After Inflammatory Lung Injury.Am J Physiol Lung Cell Mol Physiol. Jan 11. [Epub ahead of print]
27.   Zimmerman, K.M. et al. (2013) Diminished origin licensing capacity specifically sensitises tumour cells to replication stress.Mol Cancer Res. Jan 30. [Epub ahead of print]
28.   Maden, M. et al. (2013) Proliferation zones in the axolotl brain and regeneration of the telencephalon.Neural Dev. 8: 1.
 

311DS 数字振荡培养箱

品牌:美国Labnet

订货号:I-5311-DS

产品介绍

     

        311DS是一款 具有内置轨道震荡器的高性能培养箱。更大的温度范围赋予其更广泛的用途,包括液体培养、washing blots以及其他需要精确温控的震荡应用。
311DS箱体内的温度由SmartChek温控系统进行严格控制。所有的电器元件都设置在箱体以外,使其免受热压,从而实现了更长使用寿命,且无须维护保养。
整体震荡器坚固耐用,具有一个19毫米的轨道。根据需要厂家还可分别提供带防滑橡胶垫的平板和多种烧瓶置板。平板最多可放置42烧瓶和61烧瓶。
箱门上装有衬垫,并安装了一面宽大的可视玻璃面板,使用户可以透过玻璃直接查看样品。打开箱门,振荡器就会自行停止运作。

随箱配有一个层架。如需更多层架和震荡平板,可向厂商另行求购。

l         内置19mm轨道振荡器

l         独特的SmartChek温度控制系统

l         温控范围广、扩大了使用范围

l         衬垫门呈现出大而完整的视野,便于观察

 

*温度范围:

3095,分度:0.1

*温度控制精度:

±0.2

*转速:

可调,20-400rpm

*摇动方向:

轨道式,19mm

*容量:

4×2L6×1L8×500ml12×250ml20×125ml

*尺寸:

< /td>

42.5×55×58cm

*培养箱尺寸:

57.4×54.4×63.5cm

*重量:

63.6kg

 

货号

详细信息

I-5311-DS

311DS 震荡培养箱

I-5322

隔板

I-5331

架子,含放滑胶垫

I-5330

烧瓶专用架子,不含烧瓶夹

I-5330-2000

烧瓶专用架子,含 4×2000ml 烧瓶夹

I-5330-1000

烧瓶专用架子,含 6×1000ml 烧瓶夹

I-5330-500

烧瓶专用架子,含 8×500ml 烧瓶夹

I-5330-250

烧瓶专用架子,含 12×250ml 烧瓶夹

I-5330-125

烧瓶专用架子, 20×125ml 烧瓶夹

I-5330-50

烧瓶专用架子,含 30×50ml 烧瓶夹

  • 上海金畔生物科技有限公司

    文章号:258-258

异丁司特

异丁司特

货号:
II0830

品牌:
Jinpan

异丁司特

暂无详情
产品简介
含量 HPLC≥98%
MDL MFCD00864808
EC EINECS 637-150-7
InChIKey ZJVFLBOZORBYFE-UHFFFAOYSA-N
InChI InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3
PubChem CID 3671
别名 AV-411,MN-166,KC-404
CAS 50847-11-5
分子式 C14H18N2O
分子量 230.31
纯度 HPLC≥98%
单位
SMILES CC(C)C(C1=C2C=CC=CN2N=C1C(C)C)=O
靶点 Phosphodiesterase (PDE)
规格 10mg 20mg 50mg
是非选择性磷酸二酯酶(PDE)抑制剂。

0336-50G-碘乙酸钠-amresco试剂

【简单介绍】

碘乙酸钠,英文名称:IODOACETIC ACID,SODIUM SALT,等级:超纯级,包装规格:50G,CAS:305-53-3

【详细说明】

碘乙酸钠,英文名称:IODOACETIC ACID,SODIUM SALT,等级:超纯级,包装规格:50G,CAS:305-53-3

0336

IODOACETIC ACID, SODIUM SALT

Grade:ULTRA PURE GRADE

CAS Number: 305-53-3Synonym(s): None

Molecular Weight: 207.94Molecular Formula: C2H2INaO2

Storage Condition: FROZEN

CodeSizePriceQuantity

0336-10G