日度归档：2022年5月8日

2ml离心管（无色）

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2ml离心管（无色）

货号：
YA0481

品牌：
Jinpan

产品简介
单位 包
规格 500支/包 500支/包，20包/箱 500支/包，100包/箱

每包/500只 ，每箱100包。

本品没有高压灭菌，如需无菌，请在使用前高压灭菌。

Recombinant human PRKCB protein

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Recombinant human PRKCB protein

货号：
P03728

品牌：
Jinpan

产品简介
基因名 PRKCB
英文全称 protein kinase C, beta
别称 PKC-beta;PKCB;PRKCB1;PRKCB2
中文名称 蛋白激酶C,β型
Uniprot P05771
GeneID 5579
交叉反应(推测) Human Mouse Rat (Bovine Rabbit Zebrafish)
氨基酸大小 38kDa
表达氨基酸 324-673aa
Background Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation.Plays a key role in B-cell activation by regulating BCR-induced NF-kappa-B activation.Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at ‘Ser-559’, ‘Ser-644’ and ‘Ser-652’.Phosphorylation induces CARD11/CARMA1 association with lipid rafts and recruitment of the BCL10-MALT1 complex as well as MAP3K7/TAK1, which then activates IKK complex, resulting in nuclear translocation and activation of NFKB1.Plays a direct role in the negative feedback regulation of the BCR signaling, by down-modulating BTK function via direct phosphorylation of BTK at ‘Ser-180’, which results in the alteration of BTK plasma membrane localization and in turn inhibition of BTK activity.Involved in apoptosis following oxidative damage: in case of oxidative conditions, specifically phosphorylates ‘Ser-36’ of isoform p66Shc of SHC1, leading to mitochondrial accumulation of p66Shc, where p66Shc acts as a reactive oxygen species producer.Acts as a coactivator of androgen receptor (ANDR)-dependent transcription, by being recruited to ANDR target genes and specifically mediating phosphorylation of ‘Thr-6’ of histone H3 (H3T6ph), a specific tag for epigenetic transcriptional activation that prevents demethylation of histone H3 ‘Lys-4’ (H3K4me) by LSD1/KDM1A.In insulin signaling, may function downstream of IRS1 in muscle cells and mediate insulin-dependent DNA synthesis through the RAF1-MAPK/ERK signaling cascade.Participates in the regulation of glucose transport in adipocytes by negatively modulating the insulin-stimulated translocation of the glucose transporter SLC2A4/GLUT4.Phosphorylates SLC2A1/GLUT1, promoting glucose uptake by SLC2A1/GLUT1.Under high glucose in pancreatic beta-cells, is probably involved in the inhibition of the insulin gene transcription, via regulation of MYC expression.In endothelial cells, activation of PRKCB induces increased phosphorylation of RB1, increased VEGFA-induced cell proliferation, and inhibits PI3K/AKT-dependent nitric oxide synthase (NOS3/eNOS) regulation by insulin, which causes endothelial dysfunction.Also involved in triglyceride homeostasis.Phosphorylates ATF2 which promotes cooperation between ATF2 and JUN, activating transcription.
Application Immunology research
Derived from E.coli
Purification NI-NTA affinity purification
Formulation Lyophilized from a 0.2 μm filtered solution of Tris-HCl, PH8.0.
Shipping The product is shipped at -20°C temperature. Upon receipt, store it immediately at the temperature listed below.
Storage Reconstituted protein solution can be stored at 4-7°C for 1-2 months, stable at < -20°C for 2-3 years.
Reconstitution Reconstituted protein solution can be diluted with distilled PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Purity Purity≥85% as determined by reducing SDS-PAGE.
Endotoxin /
Bioactive Unknown. (Ban’t be used in biological activity experiments such as cell culture, treatment and diagnosis.)
规格 10ug 50ug 100ug 1mg

半固体营养琼脂

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半固体营养琼脂

货号：
LA3060

品牌：
Jinpan

产品简介
储存条件 常温干燥
单位 瓶
规格 250g
配制方法:
称取本品15.0g于1L蒸馏水或去离子水中，加热溶解，分装，121℃高压灭菌15分钟，摇匀备用。
配方： g/L
蛋白胨                             5.0g
牛肉粉                             3.0g
琼脂                               7.0g
pH7.0±0.1（25℃） 

Saikosaponin B2；柴胡皂苷B2

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Saikosaponin B2；柴胡皂苷B2

货号：
IS0510

品牌：
Jinpan

Saikosaponin B2；柴胡皂苷B2

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产品简介
MDL MFCD00210366
别名 柴胡皂甙B2;SaikosaponinBII
英文名称 Saikosaponin B2
CAS 58316-41-9
分子式 C42H68O13
分子量 780.98
纯度 HPLC≥98%
单位 瓶
SMILES OC[C@@]1(C)[C@]2([H])CC[C@@]3(C)[C@]4(C)C[C@@H](O)[C@@]5(CO)CCC(C)(C)CC5=C4C=C[C@]3([H])[C@@]2(C)CC[C@@H]1O[C@]6([H])O[C@H](C)[C@H](O)[C@H](O[C@]7([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@H]6O
靶点 HCV
规格 5mg 10mg 20mg
Saikosaponin B2 是柴胡根中的活性成分之一，为 HCV 病毒感染的侵入抑制剂。

牡荆素葡萄糖苷 标准品

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牡荆素葡萄糖苷 标准品

货号：
SG8530

品牌：
Jinpan

牡荆素葡萄糖苷 标准品

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产品简介
别名 Glucosyl-vitexin;
英文名称 Glucosyl-vitexin
CAS 76135-82-5
分子式 C27H30O15
分子量 594.51
储存条件 2-8℃
纯度 HPLC≥98%
外观（性状） powder
单位 瓶
SMILES O=C1C=C(C2=CC=C(O)C=C2)OC3=C1C(O)=CC(O)=C3O[C@H]4[C@H](O[C@H]5[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O5)[C@@H](O)[C@H](O)[C@@H](CO)O4
规格 20mg

Aucubin 桃叶珊瑚苷

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Aucubin 桃叶珊瑚苷

货号：
IA0660

品牌：
Jinpan

Aucubin 桃叶珊瑚苷

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产品简介
MDL MFCD00136026
EC EINECS 207-540-8
别名 杜仲甙;珊瑚苷
CAS 479-98-1
分子式 C15H22O9
分子量 346.33
纯度 HPLC≥98%
单位 瓶
SMILES O[C@H]([C@@H](O)[C@@H]1O)[C@](O[C@@H]1CO)([H])O[C@H](OC=C2)[C@@]3([H])[C@]2([H])[C@H](O)C=C3CO
靶点 TNF-α
规格 5mg 10mM*1mL (in DMSO) 10mg 50mg

是一类环烯醚萜苷，具有广泛的生物活性，包括抗炎、抗菌、抑制疼痛及抗肿瘤等活性。