曲伏前列素
| 有效期 | 2年 |
| EC | EINECS 201-001-2 |
| 描述 | 密度：1.245 g/mL |
| 别名 | 曲伏前列腺素 |
| 英文名称 | Travoprost |
| CAS | 157283-68-6 |
| 分子式 | C26H35F3O6 |
| 分子量 | 500.55 |
| 储存条件 | -20°C |
| 纯度 | ≥98% |
| 外观（性状） | Colorless to light yellow Liquid |
| 单位 | 瓶 |
| SMILES | O=C(OC(C)C)CCC/C=CC[C@@H]1[C@@H](/C=C/[C@@H](O)COC2=CC=CC(C(F)(F)F)=C2)[C@H](O)C[C@@H]1O |
| 靶点 | Prostaglandin Receptor |
| 规格 | 1mg 5mg |
小茴香油 标准品
| 英文名称 | Fennel essential oil |
| 储存条件 | RT,避光 |
| 规格 | 0.2ml |
阿德福韦酯
| 有效期 | 2年 |
| 描述 | Adefovir Dipivoxil可阻断HBV逆转录酶。 |
| EC | EINECS 200-001-8 |
| MDL | MFCD00869897 |
| InChIKey | WOZSCQDILHKSGG-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H32N5O8P/c1-19(2,3)17(26)30-11-32-34(28,33-12-31-18(27)20(4,5)6)13-29-8-7-25-10-24-14-15(21)22-9-23-16(14)25/h9-10H,7-8,11-13H2,1-6H3,(H2,21,22,23) |
| PubChem CID | 60871 |
| 别名 | 阿地福韦双吡呋酯 |
| 英文名称 | Adefovir Dipivoxil |
| CAS | 142340-99-6 |
| 分子式 | C20H32N5O8P |
| 分子量 | 501.47 |
| 储存条件 | 2-8℃ |
| 纯度 | ≥98% |
| 外观（性状） | Solid |
| 单位 | 瓶 |
| In Vitro | Adefovir dipivoxil的前基因组RNA的转录后抑制聚合酶的活性。[1] 使用鸭的HBV（DHBV）模型，Adefovir dipivoxil能够在体外和体内抑制病毒CCC DNA。Adefovir dipivoxil剂量依赖性地抑制培养上清液中病毒的释放和细胞内病毒DNA的合成。[2] 使用鸭的HBV（DHBV）模型，Adefovir dipivoxil和其他核苷类似物（lamivudine, entecavir, emtricitabine [FTC],和telbivudine [L-dT]）联用产生比单独用药更好的抗病毒效果，并且可以由布利斯独立模型表征为添加剂。Adefovir和lamivudine, FTC, 或L-dT联用时表现累积的作用，和entecavir或tenofovir联用时表现协同效应。[3] 当Adefovir加入细胞很短时间就能保留显著的抗HBV活性。[4] |
| In Vivo | Adefovir Dipivoxil降低肝脏HBV DNA至<0.1皮克乙肝病毒每转基因小鼠的总DNA（皮克/毫克）A。在转基因小鼠中，Adefovir Dipivoxil治疗还减少了血清HBV DNA至3.5 log10的基因组等同物（GE）/ mL的表达乙型肝炎病毒，相比安慰剂对照组5.3 log10的GE/毫升。Adefovir 在肝脏中，Dipivoxil的抗病毒活性在第10天达到最大值，在1.0毫克/千克/天到达的乙肝病毒抑制的端点。[1] |
| SMILES | NC1=C2N=CN(CCOCP(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)C2=NC=N1 |
| 靶点 | Reverse Transcriptase |
| 数据来源文献 | [1] Julander JG, et al. Antiviral Res, 2002, 55(1), 27-40. [2] Delmas J, et al. Antimicrob Agents Chemother, 2002, 46(2), 425-433. [3] Delaney WE 4th, et al. Antimicrob Agents Chemother, 2004, 48(10), 3702-3710. [4] Ying, et al. J Viral Hepat, 2000, 7(1), 79-83. |
| 规格 | 20mg 50mg 100mg |
【简单介绍】
上海金畔生物科技有限公司代理New England Biolabs（NEB）酶试剂全线产品，欢迎访问官网了解更多产品信息和订购。
The NEBNext® Quick Ligation Module has been optimized to ligate efficiently DNA adaptors compatible
with Illumina® sequencing to end-repaired, dA-tailed DNA fragments. The module is optimized for use with the NEBNext End Repair Module (NEB #E6050) and the NEBNext dA-Tailing Module (NEB #E6053) and is part of the original standard DNA library prep workflow, which is suitable for 1 – 5 μg of input DNA.
Quick T4 DNA Ligase
NEBNext Quick Ligation Reaction Buffer
-20°C
请联系我们。 NEBNextSelector.neb.com 可以使用在线产品选择工具进行产品选择。
女式长款短袖白大褂薄款
货号：BC013-XL-D
规格：1件/包
品牌：biosharp
商品详情：
– 全新改良，立体版型，专业量身定制，有S/M/L/XL/XXL/XXXL多种尺码可选
– 涤棉，长款短袖
– 抗皱免烫，轻松打理
– 精细做工，修身挺拔
– 简约大方,贴合人体的时尚版风格设计
| 货号 | BC013-XL-D |
| 规格 | 1件/包 |
| 品牌 | biosharp |
【简单介绍】
【详细说明】
20ul带滤芯长吸头
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Aprotinin；抑肽酶
| EC | EINECS 232-994-9 |
| MDL | MFCD00130541 |
| CAS | 9087-70-1 |
| 分子式 | C284H432N84O79S7 |
| 分子量 | 6511.44 |
| 储存条件 | 2-8℃ |
| 纯度 | ≥90% |
| 单位 | 瓶 |
| 生物活性 | Aprotinin是丝氨酸蛋白酶 (BPTI) 抑制剂，对胰蛋白酶和胰凝乳蛋白酶胰凝乳蛋白酶的 Ki 值分别为0.06 pM和9 nM。[1-6] |
| In Vitro | 抑肽酶是一种从牛肺中分离出的丝氨酸蛋白酶抑制剂, 是一种复合蛋白酶抑制剂, 具有抗纤维蛋白溶解作用, 可抑制接触激活, 并可降低对体外循环的炎症反应[2]。抑肽酶抑制胰蛋白酶 (牛, Ki = 0.06 pM) , 胰凝乳蛋白酶 (牛, Ki = 9 nM) , 纤溶酶 (人, 0.23 nM) [1]。抑肽酶也是NOS活性的竞争蛋白抑制剂。它抑制NOS-I和NOS-II, Ki值分别为50μM和78μM[3]。抑肽酶显着抑制纤维蛋白溶解, IC50为0.16±0.05μM[4]。 |
| In Vivo | 高剂量抑肽酶可以减少与原发性心脏手术相关的失血和输血要求, 如冠状动脉旁路移植术 (CABG) 或心脏瓣膜置换手术[5]。抑肽酶以剂量依赖性方式抑制血栓形成。以1.5mg kg-1 (推注) 和3mg kg-1h-1输注 (维持输注) 的剂量的抑肽酶导致出血时间减少的趋势。从3mg kg-1推注剂量加6mg kg-1h-1开始, 抑肽酶显着减少出血时间, 显示减少约84％±2.9％。在最高剂量为5 mg kg-1和10 mg kg-1 h-1时, 观察到最强的效果[4]。抑肽酶可能影响肿瘤坏死因子-α (TNF) 水平。在抑肽酶处理的野生型小鼠中I / R后可溶性TNFRI水平显着增加, 并且在所有TNFRInull小鼠中均未检测到[6]。 |
| SMILES | [RPDFCLEPPYTGPCKARIIRYFYNAKAGLCQTFVYGGCRAKRNNFKSAEDCMRTCGGA] |
| 靶点 | Serine Protease inhibitor |
| 动物实验 | 大鼠：在研究中使用雄性Wistar大鼠 (180-220g) 。将抑肽酶溶解在生理盐水中。通过推注注射然后维持输注来施用抑肽酶。给予的剂量是1.5mg kg-1和3mg kg-1h-1, 3mg kg-1和6mg kg-1h-1至5mg kg-1和10mg kg-1h-1。通过大鼠的药代动力学研究评估两种药物的血浆浓度[4]。小鼠：使用缺血/再灌注的完整小鼠模型 (30分钟-I / 60分钟-R) 并且在野生型小鼠 (WT, C57BL / 6; n = 10) , WT中测量左心室峰值+ dP / dt。具有抑肽酶 (4mL / kg; n = 10) 的小鼠, 缺乏TNFRI的转基因小鼠 (TNFRInull; n = 10) 和含有抑肽酶的TNFRInull (n = 10) [6]。 |
| 数据来源文献 | [1]. Fritz H, et al. Biochemistry and applications of aprotinin, the kallikrein inhibitor from bovine organs. Arzneimittelforschung. 1983; 33 (4) :479-94.
[2]. Levy JH, et al. Efficacy and safety of aprotinin in cardiac surgery. Orthopedics. 2004 Jun; 27 (6 Suppl) :s659-62. [3]. Venturini G, et al. Aprotinin, the first competitive protein inhibitor of NOS activity.Biochem Biophys Res Commun. 1998 Aug 10; 249 (1) :263-5 [4]. Sperzel M, et al. Evaluation of aprotinin and tranexamic acid in different in vitro and in vivo models of fibrinolysis, coagulation and thrombus formation. J Thromb Haemost. 2007 Oct; 5 (10) :2113-8. Epub 2007 Jul 31. [5]. Davis R, et al. Aprotinin. A review of its pharmacology and therapeutic efficacy in reducing blood loss associated withcardiac surgery. Drugs. 1995 Jun; 49 (6) :954-83. [6]. Sabbagh MJ, et al. Aprotinin exacerbates left ventricular dysfunction after ischemia/reperfusion in mice lacking tumor necrosis factor receptor I. J Cardiovasc Pharmacol. 2008 Oct; 52 (4) :355-62. |
| 备注 | 以上数据均来自公开文献, Jinpan暂未进行独立验证, 仅供参考。These protocols are for reference only. Jinpan does not independently validate these methods. |
| 规格 | 10mg 50mg 100mg |
是一种丝氨酸蛋白酶 (BPTI) 抑制剂。
品牌：InvivoGen
货号：psirna42-hbpi
名称：psiRNA-hBPI
InvivoGen psirna42-hbpi psiRNA-hBPI
psiRNA-BPI ：
psiRNA vector expressing shRNA targeting human BPI gene
Name: BPI
Genbank: NM_001725
Backbone: psiRNA-h7SK GFPzeo
Selection: Zeocin™
Contents：
Ready-made psiRNA-BPI plasmids are available alone or in a kit.
Each Ready-made psiRNA-BPI plasmid is provided as 20 µg of lyophilized DNA.
Each Ready-made psiRNA kit contains the following components:
– 20 µg of a Ready-made psiRNA-BPI of choice
– 20 µg of a control psiRNA plasmid (psiRNA-LucGL3)
– 1 vial of LyoComp GT116
– 4 pouches of Fast-Media© Zeo
Details：
InvivoGen psirna42-hcard8 psiRNA-hCARD8 20 µg
InvivoGen ksirna42-hcard8 psiRNA-hCARD8 Kit 1 kit
InvivoGen psirna42-hcard9 psiRNA-hCARD9 20 µg
InvivoGen ksirna42-hcard9 psiRNA-hCARD9 Kit 1 kit
InvivoGen psirna42-hcasp1 psiRNA-hCASP1 20 µg
InvivoGen ksirna42-hcasp1 psiRNA-hCASP1 Kit 1 kit
InvivoGen psirna42-hcasp8 psiRNA-hCASP8 20 µg
InvivoGen ksirna42-hcasp8 psiRNA-hCASP8 Kit 1 kit
InvivoGen psirna42-hcd14 psiRNA-hCD14 20 µg
InvivoGen ksirna42-hcd14 psiRNA-hCD14 Kit 1 kit
InvivoGen psirna42-hcd18 psiRNA-hCD18 20 µg
InvivoGen ksirna42-hcd18 psiRNA-hCD18 Kit 1 kit
InvivoGen psirna42-hcd36 psiRNA-hCD36 20 µg
InvivoGen ksirna42-hcd36 psiRNA-hCD36 Kit 1 kit
InvivoGen psirna42-hcd44 psiRNA-hCD44 20 µg
InvivoGen ksirna42-hcd44 psiRNA-hCD44 Kit 1 kit
InvivoGen psirna42-hcgas psiRNA-hcGAS 20 µg
InvivoGen ksirna42-hcgas psiRNA-hcGAS Kit 1 kit
InvivoGen psirna42-hclec9a psiRNA-hCLEC9A 20 µg
InvivoGen ksirna42-hclec9a psiRNA-hCLEC9A Kit 1 kit
InvivoGen psirna42-hcxcl16 psiRNA-hCXCL16 20 µg
InvivoGen ksirna42-hcxcl16 psiRNA-hCXCL16 Kit 1 kit
InvivoGen psirna42-hcxcr4 psiRNA-hCXCR4 20 µg
InvivoGen ksirna42-hcxcr4 psiRNA-hCXCR4 Kit 1 kit
InvivoGen psirna42-hcyld psiRNA-hCYLD 20 µg
InvivoGen ksirna42-hcyld psiRNA-hCYLD Kit 1 kit
InvivoGen psirna42-hdai psiRNA-hDAI 20 µg
InvivoGen ksirna42-hdai psiRNA-hDAI Kit 1 kit
InvivoGen psirna42-hdak psiRNA-hDAK 20 µg
InvivoGen ksirna42-hdak psiRNA-hDAK Kit 1 kit
InvivoGen psirna42-hdcsign psiRNA-hDCSIGN 20 µg
InvivoGen ksirna42-hdcsign psiRNA-hDCSIGN Kit 1 kit
InvivoGen psirna42-hddx3x psiRNA-hDDX3X 20 µg
InvivoGen ksirna42-hddx3x psiRNA-hDDX3X Kit 1 kit
InvivoGen psirna42-hddx41 psiRNA-hDDX41 20 µg
InvivoGen ksirna42-hddx41 psiRNA-hDDX41 Kit 1 kit
InvivoGen psirna42-hdectin1 psiRNA-hDectin1 20 µg
InvivoGen ksirna42-hdectin1 psiRNA-hDectin1 Kit 1 kit
InvivoGen ksirna42-hdhx9 psiRNA-hDHX9 Kit 1 kit
InvivoGen psirna42-hdnmt1 psiRNA-hDNMT1 20 µg
InvivoGen ksirna42-hdnmt1 psiRNA-hDNMT1 Kit 1 kit
InvivoGen psirna42-hdnmt2 psiRNA-hDNMT2 20 µg
InvivoGen ksirna42-hdnmt2 psiRNA-hDNMT2 Kit 1 kit
InvivoGen psirna42-hdnmt3a psiRNA-hDNMT3A 20 µg
InvivoGen ksirna42-hdnmt3a psiRNA-hDNMT3A Kit 1 kit
InvivoGen psirna42-hdnmt3b psiRNA-hDNMT3B 20 µg
InvivoGen ksirna42-hdnmt3b psiRNA-hDNMT3B Kit 1 kit
InvivoGen psirna42-hdnmt3l psiRNA-hDNMT3L 20 µg
InvivoGen ksirna42-hdnmt3l psiRNA-hDNMT3L Kit 1 kit
InvivoGen psirna42-hfadd psiRNA-hFADD 20 µg
InvivoGen ksirna42-hfadd psiRNA-hFADD Kit 1 kit
InvivoGen psirna42-hflii psiRNA-hFlii 20 µg
InvivoGen ksirna42-hflii psiRNA-hFlii Kit 1 kit
InvivoGen psirna42-hgmcsf psiRNA-hGMCSF 20 µg
InvivoGen ksirna42-hgmcsf psiRNA-hGMCSF Kit 1 kit
InvivoGen psirna42-hhdac1 psiRNA-hHDAC1 20 µg
InvivoGen ksirna42-hhdac1 psiRNA-hHDAC1 Kit 1 kit
InvivoGen psirna42-hhdac2 psiRNA-hHDAC2 20 µg
InvivoGen ksirna42-hhdac2 psiRNA-hHDAC2 Kit 1 kit
InvivoGen psirna42-hhdac3 psiRNA-hHDAC3 20 µg
InvivoGen ksirna42-hhdac3 psiRNA-hHDAC3 Kit 1 kit
InvivoGen psirna42-hhdac6 psiRNA-hHDAC6 20 µg
InvivoGen ksirna42-hhdac6 psiRNA-hHDAC6 Kit 1 kit
InvivoGen psirna42-hhdac8 psiRNA-hHDAC8 20 µg
InvivoGen ksirna42-hhdac8 psiRNA-hHDAC8 Kit 1 kit
InvivoGen psirna42-hhprt psiRNA-hHPRT 20 µg
InvivoGen ksirna42-hhprt psiRNA-hHPRT Kit 1 kit
InvivoGen psirna42-hifi16 psiRNA-hIFI16 20 µg
InvivoGen ksirna42-hifi16 psiRNA-hIFI16 Kit 1 kit
InvivoGen psirna42-hifit1 psiRNA-hIFIT1 20 µg
InvivoGen ksirna42-hifit1 psiRNA-hIFIT1 Kit 1 kit
InvivoGen psirna42-hifnar1 psiRNA-hIFNAR1 20 µg
InvivoGen ksirna42-hifnar1 psiRNA-hIFNAR1 Kit 1 kit
InvivoGen psirna42-hifnar2 psiRNA-hIFNAR2 20 µg
InvivoGen ksirna42-hifnar2 psiRNA-hIFNAR2 Kit 1 kit
InvivoGen psirna42-hikke psiRNA-hIKKε 20 µg
InvivoGen ksirna42-hikke psiRNA-hIKKε Kit 1 kit
InvivoGen psirna42-hil1r1 psiRNA-hIL1R1 20 µg
InvivoGen ksirna42-hil1r1 psiRNA-hIL1R1 Kit 1 kit
InvivoGen psirna42-hipaf psiRNA-hIPAF 20 µg
InvivoGen ksirna42-hipaf psiRNA-hIPAF Kit 1 kit
InvivoGen psirna42-hips1 psiRNA-hIPS1 20 µg
InvivoGen ksirna42-hips1 psiRNA-hIPS1 Kit 1 kit
InvivoGen psirna42-hirak1 psiRNA-hIRAK1 20 µg
InvivoGen ksirna42-hirak1 psiRNA-hIRAK1 Kit 1 kit
InvivoGen psirna42-hirak4 psiRNA-hIRAK4 20 µg
InvivoGen ksirna42-hirak4 psiRNA-hIRAK4 Kit 1 kit
InvivoGen psirna42-hirakm psiRNA-hIRAKM 20 µg
InvivoGen ksirna42-hirakm psiRNA-hIRAKM Kit 1 kit
InvivoGen psirna42-hirf1 psiRNA-hIRF1 20 µg
InvivoGen ksirna42-hirf1 psiRNA-hIRF1 Kit 1 kit
InvivoGen psirna42-hirf3 psiRNA-hIRF3 20 µg
InvivoGen ksirna42-hirf3 psiRNA-hIRF3 Kit 1 kit
InvivoGen psirna42-hirf5 psiRNA-hIRF5 20 µg
InvivoGen ksirna42-hirf5 psiRNA-hIRF5 Kit 1 kit
InvivoGen psirna42-hirf7 psiRNA-hIRF7 20 µg
InvivoGen ksirna42-hirf7 psiRNA-hIRF7 Kit 1 kit
InvivoGen psirna42-hirf9 psiRNA-hIRF9 20 µg
InvivoGen ksirna42-hirf9 psiRNA-hIRF9 Kit 1 kit
InvivoGen psirna42-hjak1 psiRNA-hJAK1 20 µg
InvivoGen ksirna42-hjak1 psiRNA-hJAK1 Kit 1 kit
InvivoGen psirna42-hkaiso psiRNA-hKAISO 20 µg
InvivoGen ksirna42-hkaiso psiRNA-hKAISO Kit 1 kit
InvivoGen psirna42-hkras psiRNA-hKRAS 20 µg
InvivoGen ksirna42-hkras psiRNA-hKRAS Kit 1 kit
InvivoGen psirna42-hku70 psiRNA-hKu70 20 µg
InvivoGen ksirna42-hku70 psiRNA-hKu70 Kit 1 kit
InvivoGen psirna42-hlamin psiRNA-hLaminA/C 20 µg
InvivoGen ksirna42-hlamin psiRNA-hLaminA/C Kit 1 kit
InvivoGen psirna42-hlc3b psiRNA-hLC3B 20 µg
InvivoGen ksirna42-hlc3b psiRNA-hLC3B Kit 1 kit
InvivoGen psirna42-hlgp2 psiRNA-hLGP2 20 µg
InvivoGen ksirna42-hlgp2 psiRNA-hLGP2 Kit 1 kit
InvivoGen psirna42-hlrrfip1 psiRNA-hLRRFIP1 20 µg
InvivoGen ksirna42-hlrrfip1 psiRNA-hLRRFIP1 Kit 20 µg
InvivoGen psirna42-hlrrfip2 psiRNA-hLRRFIP2 20 µg
InvivoGen ksirna42-hlrrfip2 psiRNA-hLRRFIP2 Kit 1 kit
InvivoGen psirna42-hmbd1 psiRNA-hMBD1 20 µg
InvivoGen ksirna42-hmbd1 psiRNA-hMBD1 Kit 1 kit
InvivoGen psirna42-hmbl2 psiRNA-hMBL2 20 µg
InvivoGen ksirna42-hmbl2 psiRNA-hMBL2 Kit 1 kit
InvivoGen psirna42-hmd2 psiRNA-hMD2 20 µg
InvivoGen ksirna42-hmd2 psiRNA-hMD2 Kit 1 kit
InvivoGen psirna42-hmda5 psiRNA-hMda5 20 µg
InvivoGen ksirna42-hmda5 psiRNA-hMda5 Kit 1 kit
InvivoGen psirna42-hmecp2 psiRNA-hMECP2 20 µg
InvivoGen ksirna42-hmecp2 psiRNA-hMECP2 Kit 1 kit
InvivoGen psirna42-hmekk3 psiRNA-hMEKK3 20 µg
InvivoGen ksirna42-hmekk3 psiRNA-hMEKK3 Kit 1 kit
InvivoGen psirna42-hmincle psiRNA-hMincle 20 µg
InvivoGen ksirna42-hmincle psiRNA-hMincle Kit 1 kit
InvivoGen psirna42-hmnda psiRNA-hMNDA 20 µg
InvivoGen ksirna42-hmnda psiRNA-hMNDA Kit 1 kit
InvivoGen psirna42-hmsk1 psiRNA-hMSK1 20 µg
InvivoGen ksirna42-hmsk1 psiRNA-hMSK1 Kit 1 kit
InvivoGen psirna42-hmul1 psiRNA-hMULAN 20 µg
InvivoGen ksirna42-hmul1 psiRNA-hMULAN Kit 1 kit
InvivoGen psirna42-hmyd88 psiRNA-hMyD88 20 µg
InvivoGen ksirna42-hmyd88 psiRNA-hMyD88 Kit 1 kit
InvivoGen psirna42-hnalp1 psiRNA-hNALP1 20 µg
InvivoGen ksirna42-hnalp1 psiRNA-hNALP1 Kit 1 kit
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