Calmodulin-Dependent Protein Kinase II(290-309) acetate

Calmodulin-Dependent Protein Kinase II(290-309) acetateCAS号： 115044-69-4分子式： C₁₀₅H₁₈₉N₃₁O₂₆S分子量： 2333.88 描述序列应用纯度储存/保存方法形态外观IC50可溶性/溶解性MDLPubChem CID

产品描述
描述	Calmodulin-Dependent Protein Kinase II (290-309) acetate is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II.
序列	Leu-Lys-Lys-Phe-Asn-Ala-Arg-Arg-Lys-Leu-Lys-Gly-Ala-Ile-Leu-Thr-Thr-Met-Leu-Ala
应用	A potent CaMKII inhibitor
纯度	>97%
储存/保存方法	Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
形态	Solid
基本信息
外观	White lyophilized solid
IC50	activation of calmodulin-dependent protein kinase II: IC₅₀ = 52 nM ; calmodulin dependent phosphodiesterase: IC₅₀ = 1.1 nM
可溶性/溶解性	Soluble in water (700 mg/L at 25 °C), chloroform (44.51 g/100mL at 25 °C), dichloromethane (19.20 g/100mL at 25 °C), methanol (9.98 g/100mL at 25 °C), DMSO (50 mM), ethanol (1.28 g/100mL at 25 °C)
MDL	MFCD00076719
PubChem CID	22114573

分子结构图

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)CAS号： 141055-85-8分子式： C₁₁₁H₁₉₁N₃₉O₂₉S₂分子量： 2600.12来源序列纯度储存/保存方法别名

产品描述
来源	Synthetic
序列	H-MET-HIS-ARG-GLN-GLU-ALA-VAL-ASP-CYS-LEU-LYS-LYS-PHE-ASN-ALA-ARG-ARG-LYS-LEU-LYS-GLY-ALA-OH
纯度	95%
储存/保存方法	-20°C，有效期2年。
基本信息
别名	(Ala286)-CaMK-II (281-302)

分子结构图

[Ala286]-Calmodulin-Dependent Protein Kinase II (281-302)

Calmodulin-Dependent Protein Kinase II (281-309)分子式： C146H254N46O39S3分子量： 3374.11储存/保存方法

产品描述
储存/保存方法	-20 ± 5 °C

CaMKI, Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain分子量： 2599.1描述序列纯度储存/保存方法别名参考文献

产品描述
描述	This is amino acids 299 to 320 fragment of the calmodulin-dependent protein kinase I (CaM kinase I) binding domain. CaM kinase I is a member of the expanding class of protein kinases that is regulated by calmodulin (CaM). This peptide is a putative CaM-bi
序列	H – Ala – Lys – Ser – Lys – Trp – Lys – Gln – Ala – Phe – Asn – Ala – Thr – Ala – Val – Val – Arg – His – Met – Arg – Lys – Leu – Gln – OH
纯度	≥ 95%
储存/保存方法	-20°C
基本信息
别名	AKSKWKQAFNATAVVRHMRKLQ
参考文献
参考文献	Yuan, t. et al. Arch. Biochem. Biophys. 421, 192 (2004).