标签归档：沙苑子

沙苑子苷A 标准品

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沙苑子苷A 标准品

货号：
SC8420

品牌：
Jinpan

沙苑子苷A 标准品

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产品简介
别名 (+)-2-顺(式),4-反(式)-脱落酸;Myricetin 3,4′-diglucoside;
英文名称 Complanatoside A
CAS 146501-37-3
分子式 C27H30O18
分子量 642.52
储存条件 2-8℃
纯度 HPLC≥98%
外观（性状） Yellow Powder
单位 瓶
SMILES O=C1C(O[C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO)=C(C3=CC(O)=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO)C(O)=C3)OC5=CC(O)=CC(O)=C15
规格 20mg

沙苑子对照药材

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沙苑子对照药材

货号：
DYS8100

品牌：
Jinpan

产品简介
储存条件 避光，密封，常温保存。
单位 瓶
规格 1g
该产品为对照药材（Reference Crude Drug），用作薄层色谱（TLC）实验的鉴别，是作为药品检验时的药材对照品使用。该产品无纯度、浓度等信息，无法做细胞实验、动物实验等用途。

沙苑子苷 A

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沙苑子苷 A

货号：
IC2940

品牌：
Jinpan

沙苑子苷 A

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沙苑子苷 A

暂无详情
产品简介
有效期 2年
描述 是一种存在于沙苑子中的一种黄酮苷，具有生物或化学活性。
英文名称 Complanatoside A
CAS 146501-37-3
分子式 C27H30O18
分子量 642.52
储存条件 -20℃
纯度 ≥98%
外观（性状） Powder
单位 瓶
In Vitro A simple and sensitive LC-MS/MS method is developed for the determination of complanatoside A in rat plasma over the range of 2.3–575 ng/mL. Complanatoside A is extracted from plasma by a protein precipitation procedure, separated by LC and detected by MS/MS in positive electrospray ionization mode. The lower limit of quantification is established at 2.3 ng/mL. Intra- and inter-day precisions (LLOQ, low-QC, med-QC and high-QC) are less than 7.9%, and accuracies are between 94.0 and 105.1%. Matrix effect is acceptable (97.9–103.0%) and extraction recovery is reproducible (88.5–94.4%). Complanatoside A is stable in the investigated conditions. The method is applied to the pharmacokinetics of complanatoside A in rats[1].
SMILES O=C1C(O[C@@H]([C@@H]([C@@H](O)[C@@H]2O)O)O[C@@H]2CO)=C(C3=CC(O)=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]4O)O)O[C@@H]4CO)C(O)=C3)OC5=CC(O)=CC(O)=C15
靶点 Others
动物实验 The assay was applied to determine the concentrations of complanatoside A in plasma samples collected from a pharmacokinetic study in rats. Six healthy male Sprague–Dawley rats (200–230 g) were used for the pharmacokinetic study. The rats were housed and handled as reported previously (Guo et al., 2015). The rats were fasted for 12 h before the experiment. Complanatoside A was formulated in water and a single dose of 30 mg/kg was administered by oral gavage. Blood samples were obtained from the vena orbitalis just prior to dose and at 0.083, 0.167, 0.25, 0.5, 0.75, 1, 2, 3, 5, 7, 10 and 14 h after administration. After centrifuga_x005ftion at 6000g for 10 min, the upper plasma was collected and stored at –20°C before analysis.[1]
数据来源文献 [1]. Li N, et al. Quantification of complanatoside A in rat plasma using LC-MS/MS and its application to a pharmacokinetic study. Biomed Chromatogr. 2016 Jun;30(6):888-93.
规格 5mg 10mg 20mg