产品货号

BE0016-2

产品规格

1/5/25/50/100mg

抗体亚型

Rat IgG2a

推荐同型对照

InVivoMAb rat IgG2a isotype control, anti-trinitrophenol（货号：BE0089）

推荐抗体稀释液

InVivoPure™ pH 7.0 Dilution Buffer（货号：IP0070）

免疫原

Recombinant mouse CD40 fusion protein

应用

in vivo CD40 activation

in vitro B cell stimulation/activation

产品形式

PBS, pH 7.0

Contains no stabilizers or preservatives

内毒素水平

<2eu>μ

in vivo CD40 activation

Bauche, D., et al. (2018). “LAG3(+) Regulatory T Cells Restrain Interleukin-23-Producing CX3CR1(+) Gut-Resident Macrophages during Group 3 Innate Lymphoid Cell-Driven Colitis.” Immunity 49(2): 342-352 e345.

in vivo CD40 activation

Bartkowiak, T., et al. (2015). “Unique potential of 4-1BB agonist antibody to promote durable regression of HPV+ tumors when combined with an E6/E7 peptide vaccine.” Proc Natl Acad Sci U S A 112(38): E5290-5299.

in vitro B cell stimulation/activation

Xu, H., et al. (2015). “Regulation of bifurcating B cell trajectories by mutual antagonism between transcription factors IRF4 and IRF8.” Nat Immunol.