(±)-氯前列烯醇钠 标准品
| 有效期 | 2年 |
| EC | EINECS:259-439-3 |
| 别名 | 氯前列醇钠；(±)-氯丁醇钠盐 |
| 英文名称 | (±)-Cloprostenol sodium salt |
| CAS | 55028-72-3 |
| 分子式 | C22H28ClNaO6 |
| 分子量 | 446.9 |
| 储存条件 | -20℃ |
| 纯度 | HPLC≥98% |
| 外观（性状） | Powder |
| 单位 | 瓶 |
| SMILES | C1[C@@H]([C@@H]([C@H]([C@@H]1O)/C=C/[C@H](COC2=CC(=CC=C2)Cl)O)C/C=CCCCC(=O)[O-])O.[Na+] |
| 规格 | 20mg |
名称：Protein A ELISA kit
货号：F400
厂家：Cygnus公司
品牌：Cygnus
规格：1 Kit
保存温度：2-8℃
货期：2～5天
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Protein A ELISA kit
蛋白质A酶联免疫试剂盒
This ELISA incorporates some improvements over the Cat. #F050 and F050H kits and is designed to better detect the newer, unnatural constructs of Protein A such as the MabSelect SuReTM ligand sold by GE Healthcare. If you are using a recombinant form of Protein A with very significant structural differences from natural Protein A such as MabSelect SuReTM you should use the Catalog #F400 kit.
Since this kit has been released, 2 newer Protein A assays, known as Mix-N-Go methods, have been developed. These new methods eliminate the sample boiling and centrifugation steps. Instead, a special sample treatment reagent is used that allows for accurate detection of Protein A in the presence of your sample antibody. The Cat. #F600 kit uses standards calibrated against natural and conserved recombinant forms of Protein A. The Cat. #F610 kit uses standards calibrated to unnatural constructs of Protein A such as GE Healthcare's MabSelect SuReTM.
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Lactococcus lactic HCP ELISA Kit F490 Host cell protein assay, 96 tests
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Polyclonal Antisera
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A549 HCP A549-PA Goat, IgG fraction
A549 HCP A549-AF Goat, affinity purified
Bovine Plasma Proteins BPP04 Rabbit, neat serum
Bovine Plasma Proteins BPP04-PA Rabbit, IgG fraction
Bovine Plasma Proteins BPP04-AF Rabbit, affinity purified
BHK HCP BHK1107 Goat, neat serum
BHK HCP BHK1107-PA Goat, IgG fraction
BHK HCP BHK1107-AF Goat, affinity purified
Campylobacter species 9-25B-PA Rabbit, IgG fraction
Campylobacter species 9-61A Guinea Pig, neat serum
Chlamydia species 8-29A Rabbit, neat serum
Chlamydia species 8-29A-PA Rabbit, IgG fraction
Chlamydia species 8-48 Guinea Pig, neat serum
CHO HCP C0016 Goat, neat serum
CHO HCP C0016-PA Goat, IgG fraction
CHO HCP C0016-AF Goat, affinity purified
CHO-CM HCP M0016 Goat, neat serum
CHO-CM HCP M0016-PA Goat, IgG fraction
CHO-CM HCP M0016-AF Goat, affinity purified
CHO HCP 3G 3G-0016 Goat, neat serum
CHO HCP 3G 3G-0016PA Goat, IgG fraction
CHO HCP 3G 3G-0016AF Goat, affinity purified
Cytomegalovirus 8-21B Rabbit, neat serum
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E. coli HCP F117 Goat, neat serum
E. coli HCP F117-PA Goat, IgG fraction
E. coli HCP AP117 Goat, affinity purified
Haemophilus influenzae 8-21A Rabbit, neat serum
Haemophilus influenzae 8-21A-PA Rabbit, IgG fraction
Haemophilus influenzae 8-53B Guinea Pig, neat serum
Haemophilus influenzae 8-53B-PA Guinea Pig, IgG fraction
HEK 293 HCP HK293 Goat, neat serum
Herpes Simplex Virus 8-25A Rabbit, neat serum
Herpes Simplex Virus 8-25A-PA Rabbit, IgG fraction
Herpes Simplex Virus 8-40B Guinea Pig, neat serum
Klebsiella pneumoniae, Genus 9-01 Rabbit, neat serum
Lactococcus lactic HCP LL5557 Goat, neat serum
Lactococcus lactic HCP LL5557-PA Goat, IgG fraction
Lactococcus lactic HCP LL5557-AF Goat, affinity purified
MRC5 HCP MRC5 Goat, neat serum
MRC5 HCP MRC5-PA Goat, IgG fraction
MRC5 HCP MRC5-AF Goat, affinity purified
Mycobacterium genus 8-27B Rabbit, neat serum
Mycobacterium genus 1-04-PA Guinea Pig, IgG fraction
Neisseria meningitidis 8-24B Rabbit, neat serum
Neisseria meningitidis 8-36 Guinea Pig, neat serum
NS/0 HCP N9192 Goat, neat serum
NS/0 HCP N9192-PA Goat, IgG fraction
NS/0 HCP N9192-AF Goat, affinity purified
PER.C6 cell line HCP PC118 Goat, neat serum
PER.C6 cell line HCP PC118-PG Goat, IgG fraction
PER.C6 cell line HCP PC118-AF Goat, affinity purified
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Pichia pastoris HCP PI-49PA Goat, IgG fraction
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Pseudomonas fluorescens 7-04 Goat, neat serum
Pseudomonas fluorescens 7-04PA Goat, IgG fraction
Pseudomonas fluorescens 7-04AF Goat, affinity purified
Pseudomonas species 8-57 Guinea Pig, neat serum
Saccharomyces cerevisiae HCP 82-SC Goat, neat serum
Saccharomyces cerevisiae HCP 82SC-PA Goat, IgG fraction
Saccharomyces cerevisiae HCP 82SC-AF Goat, affinity purified
Shigella species 9-03-PA Rabbit, IgG fraction
Shigella species 9-04 Rabbit, neat serum
SF9 HCP 12-SF9 Rabbit, neat serum
SF9 HCP 12-SF9-PA Rabbit, IgG fraction
SF21 HCP 34-SF21 Rabbit, neat serum
SF21 HCP 34-SF21-PA Rabbit, IgG fraction
SP2/0 HCP SP110 Goat, neat serum
SP2/0 HCP SP110-PA Goat, IgG fraction
SP2/0 HCP SP110-AF Goat, affinity purified
SP2/0 HCP SP110AF-B Goat, affinity purified-biotinylated
SP2/0 HCP SP110AF-AP Goat, affinity purified-alk. phosphatase
S. aureus HCP SA8114 Goat, neat serum
S. aureus HCP SA8114-AF Goat, affinity purified
Streptococcus pneumoniae 8-31B Rabbit, neat serum
Streptococcus pneumoniae 8-42A Guinea Pig, neat serum
Streptococcus pneumoniae 8-43A-PA Guinea Pig, IgG fraction
Total Goat Milk Proteins 4042 Rabbit, neat serum
Total Goat Milk Proteins 4042-PA Rabbit, IgG fraction
Total Goat Milk Proteins 4042-AF Rabbit, affinity purified
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Vero cell HCP VC807-PA Goat, IgG fraction
Vero cell HCP VC807-AF Goat, affinity purified
Stab-ELISA-rÔ Enzyme Conjugate Diluent/Stabilizers
Alkaline Phosphatase I-045 500mL
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Alk Phos w/ HAMA blocker I-040H 1000mL
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HRP w/ HAMA blocker I-035H 500mL
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Liquid Substrates
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PNPP Liquid Substrate F10008 For use with Alk Phos in ELISA, 1L
TMB Liquid Substrate F027 For use with HRP in ELISA, 100mL
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TMB Liquid Substrate F129 For use with HRP in Western Blot, 100mL
TMB Liquid Substrate F100029 For use with HRP in Western Blot, 1L
BCIP/NBT Liquid Substrate F064 For use with Alk Phos in WB, 1 reagent, 100mL
BCIP/NBT Liquid Substrate F00064 For use with Alk Phos in WB, 1 reagent, 1L
Sample Dilution Buffers
Sample Dilution Buffer, 1L， 100mL, 500mL I028 I028-100 I028-500 For use with BHK, E.coli, CHO, CHO-CM, Human IgG's, HSA, hTransferrin, HEK 293, Insulin, L.lactic, Mouse IgG's, Pichia pastoris, S.cerevisiae, Protein A, Vero cell ELISA kits
A549 Sample Diluent, 100mL , 500mL F233A-100 F233A-500 For use with A549 HCP ELISA kit
BSA Sample Dilution Buffer, 1L , 100mL , 500mL F031A / F031A-100 / F031A-500 For use with BSA, Bovine IgG, Bovine Plasma Proteins and Bovine Transferrin ELISA kits
Goat IgG Dilution Buffer, 1L , 100mL , 500mL F213A /F213A-100 / F213A-500 For use with Goat IgG ELISA kit
Goat Milk Diluent Buffer, 1L , 100mL r, 500mL F243A /F243A-100 /F243A-500 For use with Goat Milk Proteins ELISA kit
NS/0 Sample Dilution Buffer, 1L ，100mL ，500mL F223A / F223A-100 /F223A-500 For use with NS/0 HCP ELISA kit
SP2/0 Sample Dilution Buffer, 1L , 100mL , 500mL F183A / F183A-100 / F183A-500 For use with SP2/0 HCP ELISA kit
Immunogenicity Products
Passive Coated Immunogenicity Kit IM10 Kit for immunogenicity testing
Biotinylated Antigen Coated Immunogenicity Kit IM20 Kit for immunogenicity testing
Biotinylation Kit IM30
Human Immunoglobulin Screening Kit IM40 Kit for immunogenicity testing
Human IgG Subclass Kit IM50 Kit for immunogenicity testing
Substrate Kit IM109 TMB & Stop Solution for ELISA, 50mL
Coatingate Buffer, 1L IM101 For immunogenicity testing
Conjugate Diluent, 1L IM103 For immunogenicity testing
Conjugate Diluent, 500mL IM103-500 For immunogenicity testing
Sample Diluent, 500mL IM104 For immunogenicity testing
FG Blocker, 1L IM107 For immunogenicity testing
BSA Antigen, 1mg/mL IM112 For immunogenicity testing
Bovine IgG Antigen, 1mg/mL IM113 For immunogenicity testing
Bovine Transferrin Antigen, 1mg/mL IM114 For immunogenicity testing
CHO HCP Antigen, 1mg/mL IM115 For immunogenicity testing
E. coli HCP Antigen, 1mg/mL IM116 For immunogenicity testing
Goat IgG Antigen, 1mg/mL IM117 For immunogenicity testing
HSA Antigen, 1mg/mL IM118 For immunogenicity testing
Human IgD Antigen, 1mg/mL IM141 For immunogenicity testing
Human Transferrin Antigen, 1mg/mL IM119 For immunogenicity testing
Insulin Antigen, 1mg/mL IM121 For immunogenicity testing
Mouse IgG Antigen, 1mg/mL IM122 For immunogenicity testing
NS/0 HCP Antigen, 1mg/mL IM123 For immunogenicity testing
SP2/0 HCP Antigen, 1mg/mL IM125 For immunogenicity testing
Gyros Kits-discontinued
CHO 3G HCP G550 For use on the Gyros xP workstation, 560 tests
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E.coli HCP G410-1 For use on the Gyros xP workstation, 112 tests
Protein A G400 For use on the Gyros xP workstation, 560 tests
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DNA Kits
DNA Extracton in Wells D100W 96 tests in a deep well microtiter plate
DNA Extraction in Tubes D100T 50 tests in microfuge tubes
Residual CHO Host Cell kit in Wells D550W 96 tests in a deep well microtiter plate
Residual CHO Host Cell kit in Tubes D550T 50 tests in microfuge tubes
CHO Amplification kit in Wells D555W 96 tests in a deep well microtiter plate
CHO Amplification kit in Tubes D555T 50 tests in microfuge tubes
Residual Ecoli Host Cell kit in Wells D410W 96 tests in a deep well microtiter plate
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E.coli Amplification kit in Wells D415W 96 tests in a deep well microtiter plate
E.coli Amplification kit in Tubes D415T 50 tests in microfuge tubes
Residual NS/0 Host Cell kit in Wells D220W 96 tests in a deep well microtiter plate
Residual NS/0 Host Cell kit in Tubes D220T 50 tests in microfuge tubes
Miscellaneous Reagents & Components
Deep Well Extraction Plate w/Sealing Mat D102 5 plates
DNA Extraction Buffer for use in tubes D108 30mL
DNA Extraction Buffer for use in wells D105 30mL
DNA Sample Diluent D006-100 100mL
DNA Sample Diluent D006-500 500mL
DNA Sample Diluent D006-1000 1L
DNA TE Buffer, 1L D001 1L
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ENZO高敏组胺检测试剂盒
组胺是即型IgE介导过敏反映的重要介质，在机体内出现的时间非常短暂，只能在其释放的几分钟内检测到。 N-甲基组胺是组胺代谢的重要产物，存在尿液中。相比组胺有很长的半衰期 ，ENZO Histamine ELISA Kit(ENZ-KIT140) 能够同时检测组胺和代谢产物N-甲基组胺，是检测尿液中组胺水平的最佳选择。
ENZO组胺检测试剂盒特点:
● 超敏检测组胺：检测线低至0.03 ng/ml
● 无需乙酰化步骤
● 100%N-甲基组胺反应，可以检测血清、血浆中的组胺和尿液中的N-甲基组胺
● 适用范围广泛，可以检测多种样本
● 高通量检测，＜2h可以检测40个样本（做复孔）
产品信息：
详细信息请联系上海金畔生物
【简单介绍】
【简单介绍】
【详细说明】
上海金畔生物科技有限公司
文章号20042473-20042473
产品介绍：
testo 905-T1量程宽，精度高，是响应最快的插入式温度计之一。量程宽达-50到+350 °C，短时间内能到+500 °C，尤其在高量程中，testo 905-T1是同价格水平中精确度最高的产品。
| 技术参数 | |
|---|---|
|
储存温度 |
-20 ~ +70 °C |
|
操作温度 |
0 ~ +40 °C |
|
电池类型 |
3 节 AAA电池 |
|
电池寿命 |
1000 h |
|
重量 |
80 g |
|
尺寸 |
230 x 37 x 36 mm |
| 探头类型 K型热电偶 | |
|---|---|
|
量程 |
-50 ~ +350 °C |
|
精度 |
±1 °C (-50 ~ +99.9 °C) ±1%测量值 (其余量程) |
|
分辨率 |
0.1 °C |
波普瑞韦
| 有效期 | 2年 |
| 描述 | 是一种有效的选择性的 HCV NS3 protease 抑制剂。 |
| EC | EINECS 800-043-2 |
| 别名 | 伯克匹韦;SCH-503034;EBP-520 |
| 英文名称 | Boceprevir |
| CAS | 394730-60-0 |
| 分子式 | C27H45N5O5 |
| 分子量 | 519.68 |
| 储存条件 | -20℃ |
| 纯度 | ≥98% |
| 外观（性状） | Powder |
| 单位 | 瓶 |
| SMILES | O=C(N1[C@@H]([C@@]2([H])C(C)([C@]2(C1)[H])C)C(NC(C(C(N)=O)=O)CC3CCC3)=O)[C@@H](NC(NC(C)(C)C)=O)C(C)(C)C |
| 靶点 | HCV Protease |
| 规格 | 5mg 10mg |
| 商品属性 | |
|---|---|
| 商品名称 | Scientz新芝 超声波清洗机 SB-3200D-SB-3200D-新芝Scientz |
| 型号 | SB-3200D |
| 类别 | 实验室常用设备|||清洗消毒|||超声波清洗机|||Scientz新芝超声波清洗机SB-3200D |
| 品牌 | 新芝Scientz |
| 品牌简介 | 新芝Scientz |
| 关键字 | 国产台式数显超声波清洗机/器/清洗设备,可调,时间,网篮,不锈钢,仪器,壳体 |
Ellagic acid 鞣花酸
| MDL | MFCD00006914 |
| EC | EINECS 207-508-3 |
| 别名 | 倍原; ?二缩双(三羟基甲酸); lagistase |
| CAS | 476-66-4 |
| 分子式 | C14H6O8 |
| 分子量 | 302.19 |
| 纯度 | HPLC≥98% |
| 单位 | 瓶 |
| 生物活性 | Ellagic acid 是一种天然的抗氧化剂，为有效的，ATP 竞争性的 CK2 抑制剂，IC50 和 Ki 值分别为 40 nM 和 20 nM。[1-3] |
| In Vitro | 鞣花酸是一种有效的CK2抑制剂，IC50为40 nM，Ki为20 nM。鞣花酸还可以阻断其他激酶，如LYN，PKA，SYK，GSK3，FGR和CK1，IC50分别为2.9,3.5,4.3,7.5,9.4和13.0μM，对DYRK1a，CSK，NPM-没有明显影响。 ALK，RET和FLT3（IC50>40μM）。鞣花酸（5-100μM）显示出对Karpas299，SUDHL1，SR786和FE-PD细胞系的抑制活性[1]。鞣花酸（10μM）在辐射处理后对MCF-7细胞显示出细胞毒性作用。鞣花酸（10μM）与辐射（IR）组合显著地削弱了MCF-7细胞形成集落的能力，等同于单独处理。具有IR的鞣花酸还诱导细胞凋亡，并促进MCF-7细胞中前凋亡Bax的上调和Bcl-2的下调[3]。 |
| In Vivo | 鞣花酸（EA; 10mg/kg /天; po，14天）使MDA脑含量大幅降低17％，并使大鼠中TNF-α水平降低42％。鞣花酸显著增加5-HT（39％），多巴胺（DA，71％）和去甲肾上腺素（NE，77％）的脑内容物减少。鞣花酸（10 mg/kg，po，14天）导致大鼠中阿霉素诱导的组织病理学改变减少[2]。 |
| 激酶实验 | CK2和CK1磷酸化测定在37℃下在增加量的每种抑制剂（鞣花酸）存在下进行，最终体积为25μL，含有50mM，Tris-HCl pH 7.5,100mM NaCl，12mM MgCl 2，除非另有说明，否则0.02mM [33P-ATP]（500-1000cpm/pmol）。可磷酸化底物分别是CK2和CK1的合成肽底物RRRADDSDDDDD（100μM）和RRKHAAIGDDDDAYSITA（200μM）。加入激酶开始反应，10分钟后停止反应。在将等分试样点到磷酸纤维素滤膜上之前，加入5μL的0.5M正磷酸。在放射性标记的样品的SDS-PAGE后，在75mM磷酸底物中洗涤滤膜。 DYRK1A，肽RRRFRPASPLRGPPK测定，酪氨酸激酶活性测定[1]。 |
| SMILES | O=C1C2=CC(O)=C(O)C(O3)=C2C4=C(C3=O)C=C(O)C(O)=C4O1 |
| 靶点 | Casein Kinase（CK） |
| 动物实验 | 将50只雄性成年Sprague-Dawley大鼠随机分成如下五组：组（1）口服玉米油作为载体并用作正常对照。组（2）每周两次接受多柔比星（DOX）注射（5mg/kg，ip），持续14天。组（3）每天两次接受鞣花酸（10mg/kg，po;每天）14天，并且每周两次接受DOX（5mg/kg，ip）持续14天。组（4）每天两次接受迷迭香酸（RA; 75mg/kg，po;每天）14天，并且每周两次接受DOX（5mg/kg，ip）持续14天。组（5）接受鞣花酸（10mg/kg，po;每天），RA（75mg/kg，po;每天）14天，DOX注射（5mg/kg，ip），每周两次，持续14天[ 2]。 |
| 细胞实验 | 通过MTT测定法测量ALCL细胞活力。简而言之，在加入鞣花酸之前12小时将0.1×10 5个细胞接种到96孔微量培养板上。在存在或不存在药物（鞣花酸）的情况下，在标准组织培养条件下，将细胞在200μL完全RPMI-1640培养基中生长48小时。然后将20μLMTT溶液（5mg/mL）加入细胞悬浮液中4小时。用150μLDMSO溶解细胞内甲crystals晶体，在分光光度计上在540nm处测量的光密度代表一式三份培养物的平均值（±SD）[1]。 |
| 数据来源文献 | [1]. Cozza G, et al. Identification of ellagic acid as potent inhibitor of protein kinase CK2: a successful example of a virtual screening application. J Med Chem. 2006 Apr 20;49(8):2363-6.
[2]. Rizk HA, et al. Prophylactic effects of ellagic acid and rosmarinic acid on doxorubicin-induced neurotoxicity in rats. J Biochem Mol Toxicol. 2017 Dec;31(12). [3]. Ahire V, et al. Ellagic Acid Enhances Apoptotic Sensitivity of Breast Cancer Cells to γ-Radiation. Nutr Cancer. 2017 Aug-Sep;69(6):904-910. |
| 规格 | 10mg 50mg |
是一种抗氧化剂，为有效的，ATP 竞争性的 CK2 抑制剂。
使用本产品应用案例:
文章：The protective effect of Ellagic acid (EA) in osteoarthritis: An in vitro and in vivo study. Biomed Pharmacother. 2020 May;125:109845.
作者：Lin Z, Lin C, Fu C, Lu H, Jin H, Chen Q, Pan J.
doi: 10.1016/j.biopha.2020.109845. Epub 2020 Feb 12. PMID: 32058211.
摘要：
骨关节炎（OA）是一种进行性关节疾病，其主要特征是关节软骨的退化和破坏。鞣花酸 (EA) 是一种在浆果和坚果中发现的天然多酚，已显示出有效的抗炎作用，然而，它对 OA 的作用和潜在机制却很少被系统地阐明。在这项研究中，我们在体外和体内实验中报告了鞣花酸 (EA) 在 OA 进展中的抗炎作用。体外研究，IL-1β 诱导的诱导型一氧化氮合酶 (iNOS)、环氧合酶-2 (COX-2)、一氧化氮 (NO)、肿瘤坏死因子-α (TNF-α)、前列腺素 E2(PGE2) 的表达, 和白细胞介素 6 (IL-6) 被鞣花酸 (EA) 抑制。此外，鞣花酸 (EA) 下调 IL-1β 刺激的基质金属蛋白酶 13 (MMP-13) 和血小板反应蛋白基序 5 (ADAMTS-5)，同时上调 II 型胶原蛋白和聚集蛋白聚糖。从机制上讲，我们发现鞣花酸 (EA) 抑制 IL-1β 诱导的软骨细胞中的核因子 kappa B (NF-κB) 信号传导。 DMM模型也显示了鞣花酸（EA）诱导的OA发展保护作用。总之，我们的数据表明鞣花酸 (EA) 可作为 OA 治疗的潜在药物。
方案：
Cell viability
Firstly, passages 3 chondrocytes were seeded into 96-well plates (5,000 cells/well) and incubated for 24 h. Then, the cells incubated with a concentration gradient (12.5, 25, 50 μM) of Ellagic acid (EA) for 24 h and 48 h when the cells reached a confluency of 90 %–95 %. Next, half the cells were incubated in IL-1β (10 ng/ml) for the next 24 h.Finally, 10 μl CCK-8 solution was added to each well for 2 h and the optical density was observed at 450 nm with a spectrophotometer . All experiments were repeated three times.
Animals
The mouse osteoarthritis model was established by surgical destabilization of the medial meniscus (DMM). In brief, mice were anesthetized with intraperitoneal injection of 2 % (w/v) pentobarbital (40 mg kg−1,) and then the joint capsule of right knee medial to the patellar tendon was excised. The medial meniscotibial ligaments were cut with microsurgical scissors. Surgery consisting of an arthrotomy was also performed on the left knee joint of mice and the joint was used as the sham group. Ultimately, all of the mice were separated into three groups randomly (n = 15 in each): a control group (sham-operated), OA group (OA) and OA treated with Ellagic acid (EA) group.
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10%NaCl胰酪胨大豆肉汤
| 英文名称： | |
| 产品货号： | JPJ4114-90 |
| 产品规格： | 10个/盒 |
| 保质期： | 一年 |
| 产品用途： | 用于金黄色葡萄球菌的增菌培养 |
| 备 注： |
产品介绍:
用途：用于金黄色葡萄球菌的增菌培养
10%NaCl胰酪胨大豆肉汤微生物灵敏度试验:
按标签用法制备培养基，接种以下质控菌株，
放置36±1℃需氧培养18-24小时。
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【简单介绍】
【详细说明】
